摘要
目前，大量临床流行病学的研究认为，幽门螺杆菌与多种皮肤病可能具有相关性。幽门螺杆菌引起皮肤病的病理生理基础可能是其感染后诱导炎症介质及细胞因子释放进而引发的一系列自身免疫反应所致，幽门螺杆菌可能是这些皮肤病的病因也可能是发病的协同因素，然而由于流行病学研究的局限性以及缺乏具有说服力的机制研究，也存有争议。为此，文中概述幽门螺杆菌与多种皮肤病的相关研究，为进一步研究和皮肤病的诊治带来新的思路。
A large number of clinical epidemiological studies have suggested that Helieobacter pylori is somewhat associated with dermatologic diseases. Helicobacter pylori infection may induce the release of inflammatory mediators and cytokines followed by the initiation of autoimmune response, which is considered to be the pathophysiological basis of dermatologic diseases associated with Helicobacter pylod. In the pathogenesis of these skin diseases,Helieobacter pylori may function as either a direct cause or a synergistic factor. However, there has been no convincing evidence for the relationship between Helicobacter pylori and dermatologic diseases because of the limitations of epidemiological studies as well as the lack of rigorous studies on disease mechanisms. The authors review recent research into the correlation between Helicobacter pylori and several skin disorders, which may bring new ideas to the diagnosis and treatment of relevant skin diseases.
出处
《国际皮肤性病学杂志》
2013年第2期124-127,共4页
International Journal of Dermatology and Venereology
