摘要
目的探讨布地奈德雾化吸入治疗急性感染性喉炎临床疗效。方法对我院儿科收住的80例急性感染性喉炎,据治疗方法不同分为治疗组与对照组,两组均给予综合治疗。治疗组给予布地奈德(0.5 mg/次,2次/日)雾化吸入;对照组给予地塞米松(0.3～0.5 mg/kg.d)静脉滴注,疗程3天,观察两组治疗后临床疗效。结果治疗组治疗后2 h就能改善临床症状,治疗组治疗后2、6 h症状评分优于对照组(P<0.05),而12、24、48 h两组症状评分经比较差异无统计学意义(P>0.05)。两组72 h治愈率差异无统计学意义(χ2=0.74,P=0.15)。结论布地奈德雾化吸入治疗急性感染性喉炎能迅速改善临床症状,疗效确切。
Objective To investigate the clinical effect of budesonide inhalation in the treatment of patients with acute infectious laryngitis. Methods 80 patients with acute infectious laryngitis were all given conventional treatment and then were divided into two groups according to the different treatment methods. The treatment group received budesonide inhalation 0. 5 rag every time and twice a day. The control group was intravenously injected with dexamethasone （0. 3 ～ 0. 5 mg/kg · d）. The course of treatment was three days. The clinical efficacy was observed. Results The clinical symptoms of the treatment group were improved 2 hours after the treatment. The symptom scores at 2-hour and 6-hour after the treatment were better in the treatment group than in the control group （ P 〈 0. 05 ）, but the symptom scores at 12-hour, 24-hour, 48-hour after the treatment showed no significant difference between the two groups （ P 〉 0.05 ）. The cure rate at 72-hour after the treatment had no statistical significance （ X2 = 0. 7410 P = 0. 1499 P 〉 0. 05 ）. Conclusion Budesonide inhalation can rapidly improve the clinical symptoms and have a favorable curative effect in the treatment of patients with acute infectious laryngitis.
出处
《临床肺科杂志》
2013年第4期641-642,共2页
Journal of Clinical Pulmonary Medicine
关键词
急性喉炎
布地奈德
雾化吸入
acute infectious laryngitis
budesonide
inhalation
