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延长聚乙二醇干扰素α-2a疗程治疗CHB获得高水平HBsAg/HBsAb转换一例 被引量:1

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摘要 本文就1例HBeAg阳性慢性乙型肝炎患者长疗程运用长效干扰素治疗的效果进行总结。患者在应用聚乙二醇干扰素α-2a达到1年标准化治疗后,延长治疗至120周,出现>1000 IU/L的高水平表面抗体应答。曾于治疗前、中、末三次肝穿活检确定疗效,动态观察肝组织内部病理改变情况。本例具有HBsAg下降快,HBsAb应答水平高的特点。延长疗程至120周后,HBsAb达706 IU/L,停药后30周继续递增至1000 IU/L以上,为临床罕见。
作者 程书权 张磊
出处 《中国处方药》 2013年第1期51-53,共3页 Journal of China Prescription Drug
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