摘要
目的:观察中药活血散结方对肝硬化门静脉系统血流动力学的影响。方法:90例肝硬化门静脉高压患者随机分为两组,对照组(46例)予口服心得安治疗,治疗组(44例)口服心得安,同时肝区外敷中药活血散结方,每天1次,两组疗程均为1个月。治疗前后采用彩色超声仪观察门、脾静脉血流动力学变化。结果:对照组治疗后门静脉内径较治疗前缩小(P<0.05),但脾静脉内径无明显变化,对照组治疗后门静脉、脾静脉的平均流速和流量无明显变化;治疗组治疗后门静脉、脾静脉内径均较治疗前明显缩小,门静脉、脾静脉平均流速和流量的明显降低,与对照组治疗后比较有显著性差异(P<0.05)。结论:活血散结方肝区封包可明显降低肝硬化患者门静脉、脾静脉压力,改善门静脉血流动力学状态,提高心得安疗效。
Objective： To observe the effects of Huoxue Sanjie decoction on hepatic cirrhotic portal system hemodynamics. Method： Ninty cases of cirrhotic portal hypertension were randomly divided into two groups, control group （n=46） received oral propranolol therapy, the treatment group （n=44） oral propranolol, but liver area external application of Chinese medicine Huoxue Sanjie decoction, 1 times a day, two groups were treated for 1 months.Before and after treatment using color ultrasound observation portal venous hemodynamic changes. Result： The control group treated with portal vein diameter was reduced after treatment （P〈0.05）, but no significant changes in the diameter of splenic vein, the control group treated with portal vein, splenic vein of the mean velocity and flow volume did not change significantly; treatment group treatment of portal vein, splenic vein were significantly reduced, portal vein, splenic vein and average flow velocity flow was significantly reduced, and the comparison of the two groups had significant difference （P〈0.05）. Conclusion： Chinese medicine Huoxue Sanjie decoction on liver packet can significantly decrease in patients with liver cirrhosis portal vein, splenic vein pressure, improve the portal vein hemodynamic status, improve the therapeutic effect of propranolol.
出处
《中国实验方剂学杂志》
CAS
北大核心
2013年第6期298-300,共3页
Chinese Journal of Experimental Traditional Medical Formulae
关键词
肝硬化
活血散结方
门静脉高压
门静脉血流动力学
Liver cirrhosis
Huoxue Sanjie decoction
portal hypertension
portal vein hemodynamics
