血微小RNA水平与肺动脉高压关系的研究进展
被引量:1
Research progress of the relationship of blood micro RNA levels and pulmonary arterial hypertension
摘要
微小RNA(microRNA,miRNA)是一类约高度保守的小分予非编码RNA,具有调控细胞分化、增殖、凋亡的功能,与心血管疾病密切相关。因肺动脉高压是血管增殖性疾病,
出处
《中国心血管病研究》
CAS
2013年第2期150-153,共4页
Chinese Journal of Cardiovascular Research
关键词
微小RNA
肺动脉高压
先天性心脏病
Micro RNA
Pulmonary arterial hypertension
Congenital heart disease
参考文献25
-
1Lee RC, Ambros V. The C, elegans heterochronie gene lin-4 en-codes small RNAs with antisense complementarity to lin -14.Cell, 1993,75:843-854. 被引量:1
-
2王泽,鲍贤豪,秦升.微小RNA在心血管疾病中的意义及临床应用[J].中国心血管病研究,2011,9(6):471-474. 被引量:5
-
3沙莎,陈月云(审校).MicroRNAs与心肌缺血再灌注损伤[J].中国心血管病研究,2012,10(11):867-870. 被引量:2
-
4Wu W, Sun M, Zou GM, et al. Micro RNA and cancer:currentstatus and prospective. Int J Cancer, 2007,120 : 953-960. 被引量:1
-
5Cheng Y, Ji R, Yue J, et al. MicroRNAs are aberrantly ex -pressed in hypertrophic heart : do they play a role in cardiac hy-pertrophy? Am J Pathol,2007,170: 1831-1840. 被引量:1
-
6Care A,Catalucci D, Felicetti F,et al. MicroRNA-133 controlscardiac hypertrophy. Nat Med,2007,13 :613-618. 被引量:1
-
7Barker DJ, The Wellcome Foundation Lecture. The fetal origins ofadult disease. Proc Biol Sci, 1995,262: 37-43. 被引量:1
-
8Lucas A. Programming by early nutrition in man. Cib a Founda-tion symposium, 1991,156:38-55. 被引量:1
-
9Brawley L, Torrens C, Anthony FW, et al. Glycine rectifies vas-cular dysfunct - ion induced by dietary protein imbalance duringpregnancy. J Physiol, 2004,554 : 497-504. 被引量:1
-
10Brawley L, Itoh S, Torrens C, et al. Dietary protein restrictionin pregnancy induces hypertension and vascular defects in ratmale offspring. Pediatr Res, 2003,54 : 83-90. 被引量:1
二级参考文献71
-
1张俊义,闫素华.心肌梗死后心律失常研究的新进展——交感、副交感神经失衡[J].中国心血管病研究,2009,7(9):705-709. 被引量:6
-
2杨水祥,胡大一,唐朝枢.基因组学研究的革命性工具——小分子RNA研究进展(一)[J].中国心血管病研究,2004,2(12):923-925. 被引量:8
-
3张璞,肖传实.心血管疾病基因治疗[J].中国心血管病研究,2006,4(5):394-396. 被引量:5
-
4Du T, Zamore PD. microPrimer: the biogenesis and function of microRNA. Development 2005;132(21): 4645-52. 被引量:1
-
5Alvarez-Garcia I, Miska EA. MicroRNA functions in animal development and human disease. Development 2005; 132(21): 4653-62. 被引量:1
-
6Lovis P, Gattesco S, Regazzi R. Regulation of the expression of components of the exocytotic machinery of insulin-secreting cells by microRNAs. Biol Chem 2008; 389(3): 305-12. 被引量:1
-
7Chen Y, Gorski DH. Regulation of angiogenesis through a microRNA (miR-130a) that down-regulates antiangiogenic homeobox genes GAX and HOXA5. Blood 2008; 111(3): 1217-26. 被引量:1
-
8Kuehbacher A, Urbich C, Zeiher AM, Dimmeler S. Role of Dicer and Drosha for endothelial microRNA expression and angiogenesis. Circ Res 2007; 101(1): 59-68. 被引量:1
-
9Brock M, Trenkmann M, Gay RE, Michel BA, Gay S, Fischler M, et al. Interleukin-6 modulates the expression of the bone morphogenic protein receptor type II through a novel STAT3-microRNA cluster 17/92 pathway. Circ Res 2009; 104(10): 1184-91. 被引量:1
-
10Rabinovitch M. Molecular pathogenesis of pulmonary arterial hypertension. J Clin Invest 2008; 118(7): 2372-9. 被引量:1
共引文献11
-
1陈伟丹,聂宇,李守军.循环miR-19a作为先天性心脏病相关肺动脉高压的标志物[J].中国分子心脏病学杂志,2010,10(5):285-288. 被引量:12
-
2姜新民,张忠房,邵贝贝.miRNAs及其在医学领域的研究进展[J].医学检验与临床,2012,23(1):55-58.
-
3李颖庆,卢建华,王西富,李欣,胡春林,廖晓星.心肌特异性miR-133a与cTnT早期诊断急性心肌梗死的价值[J].中国心血管病研究,2014,12(1):4-8. 被引量:3
-
4彭晓,王志伟,苟德明.microRNAs与心血管疾病的研究进展[J].中华临床医师杂志(电子版),2013,7(14):184-185. 被引量:4
-
5吕宁,戴海龙,尹小龙.先天性心脏病相关性肺动脉高压患者血miR-18a、miR-27b、miR-130a、miR-204水平研究[J].中国心血管病研究,2014,12(9):785-788. 被引量:4
-
6何观虹,姚丽.MicroRNA在肺动脉高压发病机制中作用的研究进展[J].中国医药生物技术,2015,10(2):167-171. 被引量:1
-
7陈宏,陈群,齐鑫,于婷婷,吴士明,苏玉明.microRNA-184在小儿先天性心脏病中的表达及其与心肌细胞的关系[J].医学分子生物学杂志,2017,14(1):18-21. 被引量:4
-
8窦京彬,王娜娜,张红明.微小RNA在心肌缺血/再灌注损伤中保护作用及机制的研究进展[J].中国心血管病研究,2017,15(10):873-876. 被引量:2
-
9郭建洲,王志伟,马琰琰.血浆miRNA在先天性心脏病继发肺动脉高压的差异表达[J].心脏杂志,2018,30(4):442-445. 被引量:4
-
10李晖,徐金升.慢性肾脏病血管钙化机制的研究进展[J].中国心血管病研究,2018,16(10):873-878. 被引量:3
同被引文献39
-
1Chistiakov DA, Orekhov AN, Bobryshev YV. Vascular smooth muscle cell in atherosclerosis. Acta Physio, 2015,214 : 33-50. 被引量:1
-
2Maegdefessel L, Rayner KJ, Leeper NJ. MicroRNA regulation of vascular smooth muscle function and phenotype: early career committee contribution. Arterioscler Thromb Vasc Biol, 2015,35 : 2-6. 被引量:1
-
3Owens GK, Kumar MS, Wamhoff BR. Molecular regulation of vascular smooth muscle cell differentiation in development and disease. Physio Rev, 2004,84 : 767-801. 被引量:1
-
4Raines EW, Ross R. Smooth muscle cells and the pathogenesis of the lesions of atherosclerosis. Bri Heart J, 1993,69 : $30-37. 被引量:1
-
5Ten Dijke P, Arthur HM. Extracellular control of TGFbeta sig- nalling in vascular development and disease. Nat Rev Mol Cell Biol, 2007,8 : 857-869. 被引量:1
-
6Mendell JT, Olson EN. MicroRNAs in stress signaling and human disease. Cell, 2012,148 : 1172-1187. 被引量:1
-
7Robinson HC, Baker AH. How do microRNAs affect vascular smooth muscle cell biology? Curt Opin Lipidol, 2012,23:405 - 411. 被引量:1
-
8Small EM, Frost ILl, Olson EN. MicroRNAs add a new dimen- sion to cardiovascular disease. Circulation, 2010, 121 : 1022-1032. 被引量:1
-
9Song Z, Li G. Role of specific microRNAs in regulation of vascu- lar smooth muscle cell differentiation and the response to injury. J Cardiovasc Transl Res, 2010,3 : 246-250. 被引量:1
-
10Albinsson S, Sessa WC. Can micmRNAs control vascular smooth muscle phenotypic modulation and the response to injury? Physiol Genomics, 2011,43 : 529-533. 被引量:1
-
1赵健,刘斌.紫杉醇的作用机制及在血管增殖性疾病中的应用[J].西南军医,2013,15(4):415-419.
-
2段超,陈鑫,邱志兵.血管外膜成纤维细胞与血管再狭窄[J].心脏杂志,2010,22(2):285-288. 被引量:1
-
3汪明慧,许顶立,赖文岩.细胞周期调控机制与血管增殖性疾病的防治[J].医学与哲学,2001,22(10):34-36.
-
4张俊霞.核酶在血管增殖性疾病中的应用[J].国外医学(生理病理科学与临床分册),2003,23(1):50-52. 被引量:3
-
5谭元生,唐文利.中药调控高血压血管平滑肌细胞增殖的研究进展[J].中西医结合心脑血管病杂志,2014,12(7):874-876.
-
6段超,陈鑫,邱志兵.JAK-STAT信号传导通路和血管平滑肌细胞[J].心血管病学进展,2009,30(6):1056-1058.
-
7廖华,糜涛,郭小梅.血管平滑肌细胞增殖信号转导通路与血管再狭窄防治[J].医药导报,2007,26(2):116-120. 被引量:6
-
8侯磊.P27对血管平滑肌细胞增殖的调控[J].同济大学学报(医学版),2002,23(6):529-531.
-
9胡榕,吴可贵.凝血酶及其受体在血管平滑肌细胞增殖中的作用[J].高血压杂志,2004,12(4):283-286. 被引量:4
-
10黄捷,冯艳,韩凌,李艳,张晶晶,宋昆鹏,石海莉.核糖核酸干扰基质金属蛋白酶-3基因对大鼠血管平滑肌细胞增殖的影响[J].中国循环杂志,2015,30(2):159-163. 被引量:7