摘要
目的探讨缺血性脑卒中和踝臂指数(ankle-brachial index,ABI)的关系。方法 2008年10月至2010年10月就诊的414例急性缺血性脑卒中患者为病例组,92例急性脑出血患者为对照组,通过简化方法测量其踝臂指数,同时收集相关资料。运用SPSS 14.0软件建立数据库,并进行统计学处理。结果病例组ABI<0.9有33例,对照组0例,病例组ABI中值是1.030 0,四分位距0.16;对照组ABI中值是1.156 5,四分位距0.14。单因素Logistic回归分析显示,缺血性脑卒中与ABI<0.9(OR=3.364,CI:2.607～4.339,P<0.001)、年龄(OR=3.218,CI:2.512～4.123,P<0.001)、高血压(OR=20.918,CI:11.747～37.249,P<0.001)、糖尿病(OR=4.340,CI:1.948～9.669,P<0.001)、心脏病(OR=2.539,CI:1.408～4.579,P=0.002)、肥胖(OR=4.324,CI:1.536～12.174,P=0.006)、酗酒(OR=0.498,CI:0.255～0.973,P=0.041)相关。多因素logistic回归分析显示,缺血性脑卒中与高血压(OR=11.332,CI:5.941～21.613,P<0.001)、年龄(OR=2.519,CI:1.852～3.425,P<0.001)、ABI<0.9(OR=0.020,CI:0.002～0.186,P<0.001)、肥胖(P=0.007,OR=5.967,CI:1.641～21.692)、糖尿病(OR=2.515,CI:0.984～6.431,P=0.054)相关。结论简化方法测得ABI<0.9与缺血性脑卒中相关,ABI<0.9、年龄、高血压、肥胖和糖尿病是缺血性脑卒中的独立危险因素。
Objective To investigate the relationship between ischemic stroke and ankle-brachial index （ABI）. Methods A total of 414 patients with acute ischemic stroke （case group） and 92 cases of acute cerebral hemorrhage （control group） were admitted from October 2008 to October 2010. The ABI was measured with simplified method. The clinical data were analyzed by SPSS 14.0 software. Results There were 33 cases with ABI 〈 0.9 in case group, there was no case of ABI 〈 0.9 in control group. In case group, the median of ABI was 1. 030 0 with an interquartile range of 0.16 ; meanwhile, in control group, the median of ABI was 1. 1565 with an interquartile range of 0. 14. Univariate logistic regression analysis showed that the risk factors for ischemic stroke were ABI 〈 0.9 （OR = 3. 364, CI =2. 607 - 4. 339, P 〈 0. 001）, age （OR = 3. 218, CI = 2. 512 - 4. 123, P 〈 0. 001）, hypertension （OR = 20. 918, CI = 11. 747 - 37. 249, P 〈 0. 001）, Diabetes （OR = 4. 340, CI = 1. 948 - 9. 669, P 〈 0.001 ）, heart disease （ OR = 2.539, CI = 1. 408 - 4.579, P = 0.002）, obesity （ OR =4. 324, CI = 1. 536 - 12.174, P =0.006） alcoholism （ OR =0.498, CI =0.255 -0.973, P = 0.041 ）. Multivariate logistic regression analysis showed that hypertension （OR = 11. 332, CI = 5. 941-21.613, P〈0.001）, age （OR=2.519, CI=1.852-3.425, P〈0.001）, ABI〈0.9 （OR = 0. 020, CI = 0. 002 - 0.186, P 〈 0. 001 ）, obesity （ OR = 5. 967, CI = 1. 641 - 21. 692, P = 0. 007）, diabetes （OR =2. 515, CI =0.984 -6.431, P =0.054） were the risk factors for ischemic stroke. Conclusion ABI 〈 0.9 （by simplified method） is independent risk factor for ischemic stroke along with age, hypertension, alcoholism, obesity and diabetes.
出处
《同济大学学报（医学版）》
CAS
2013年第1期81-84,共4页
Journal of Tongji University(Medical Science)
基金
上海市虹口区卫生局课题(虹卫0803-08)
