摘要
目的观察经纤维支气管镜治疗难治性肺炎的临床疗效。方法对40例（治疗组）难治性肺炎患者在常规治疗的基础上经纤维支气管镜行局部灌洗、吸痰和注药等治疗，并与同期仅行常规治疗的22例（对照组）难治性肺炎患者相比较。观察比较两组临床治疗效果。结果对照组有效率54．5％，治疗组有效率85．0％，治疗组有效率明显高于对照组（X2=8．511，P=0．0140）。治疗组治疗后体温为（36．5±2．0）℃，明显低于对照组的（37．9±3．0）℃（t=2．1996，P=0．0317）；胸片或CT显示病灶好转时间治疗组为（12．3±2．1）d，明显少于对照组的（16．0±1．3）d（t=7．3844，P：0．0000）；治疗组痰量变化为（79．7±8．6）ml，明显高于对照组的（34．6±7．8）ml（t=20．3792，P=0．0000）；治疗组住院时间为（20．3±3．1）d，明显少于对照组的（27．0±6．3）d（t=5．6700，P=0．0001）。结论经纤维支气管镜局部灌洗、吸痰和注药治疗难治性肺炎能明显提高疗效及缩短病程，改善预后。
Objective To study the efficacy of bronchoalveolar lavage and drug injection by bronchofibro- scope in patients with refractory pneumonia. Methods 62 cases with refractory pneumonia were divided into therapy group（40 cases） and control group（22 cases）. All patiens were treated with conventional therapy, bronchoalveolar lavage and drug injection by bronchofibroscope were treated for patients in therapy group in addition. Therapeutic effects were compared between two groups： Results The effective rates of therapy group were significantly higher than that in control group （ 85.0% vs 54.5 %, X2 - 8.511, P = 0. 014）. The control of temperature, amount of sputum, absorption of the lesions and hospitalization days in therapy group were better than those in control group （ all P 〈 0. 05 ）. Conclusion Bronchoalveolar lavage and drug injection by bronchofibroscope is effective for patients with re- fractory pneumonia, which can shorten the course of treatment, improve prognosis, and deserve the clinical expansion.
出处
《中国基层医药》
CAS
2013年第6期830-832,共3页
Chinese Journal of Primary Medicine and Pharmacy
