摘要
目的:分析不同炎症性肠病(inflammatory bowel diseasw,IBD)患者组C反应蛋白(Creactive protein,CRP)异常人数及治疗前、治疗后CRP的变化水平,探讨CRP在炎症性肠病中的诊断及评估治疗的作用。方法:采用透射免疫比浊法检测所有入选对象的CRP水平及治疗病情稳定后其CRP水平。结果:CRP异常人数在IBD活动组明显升高,差异有统计学意义;治疗前IBD活动组患者CRP水平较其他各组明显增高,活动组IBD患者治疗后的和治疗前相比CRP水平显著下降。所有IBD患者治疗后CRP水平和其他各组相比差异不大。结论:CRP水平对活动期IBD患者的诊断虽特异性不强但能简单的区分IBD的严重程度,可作为活动期IBD的辅助诊断、病情判断、疗效评估的一个重要指标。
Objective：To study the level of C - reactive protein in different groups of IBD and evaluate the role of CRP in the diagnosis and treatment of IBD. Methods： Transmitted immunoturbidimetry assay was employed to de- tect the CRP levels in patients with inflammatory bowel disease before and after treatment. Results： The number of patient with abnormal CRP in active IBD group was larger than other groups, the difference was statistically signifi- cant. The level of CRP in active IBD group was higher than other groups before treatment. CRP in serum of patient with active IBD declined after proper treatment. All patients have a same level compared to other groups after treat- ment. Conclusion： Ahhough the specificity of CRP in diagnosis of active IBD patients is not strong, it is simple to distinguish the severity of IBD and can be used as a auxiliary diagnostic index for IBD in active phase. In addition, CRP is an important indicator to evaluate the condition of IBD and the therapeutic effect.
出处
《中国卫生检验杂志》
北大核心
2013年第2期395-396,共2页
Chinese Journal of Health Laboratory Technology
关键词
C反应蛋白
炎症性肠病
溃疡性结肠炎
克隆恩病
C -reactive protein
hfflammatory bowel disease
Ulcerative colitis
Crohn disease
