摘要
目的探讨抑郁症患者交感神经皮肤反应(SSR)的特点及其与焦虑抑郁严重程度的相关性。方法对32例首发抑郁症、19例复发抑郁症和27例正常对照组分别检测SSR潜伏期和波幅。结果首发抑郁症和复发性抑郁症患者的双侧上下肢SSR波潜伏期和波幅与正常组相比,差异均无统计学意义(P>0.05),但复发性抑郁症的左上肢SSR波潜伏期显著长于首发稀有症(P=0.034);抑郁症的双侧上下肢SSR波潜伏期和波幅与HAMD、HAMA的评分,其差异均无统计学意义(P>0.05)。结论 SSR可能并不能敏感地反映抑郁症的自主神经功能损害症状,因而其临床应用价值也尚不能肯定。
Objective To explore the feature of sympathetic skin reaction （SSR） and its correlation between anxiety - depression level in patients with major depressive disorder. Methods Comparing 32 individuals with first episode depression, 19 individuals with relapse depression and 27 control individuals, then detecting the latency and amplitude of SSR respectively. Results Patients with primary depression and relapse depression have no significant discrepancy in the latency and amplitude of SSR in the bilateral upper and lower limbs, compared with normal control individuals（ P 〉 0. 05 ）. However, the latency of SSR in the left upper extremity of relapse depression is remarkably longer than primary depression （ P = 0. 034）. Moreover, the latency and ampli- tude of SSR in the bilateral upper and lower limbs of depressive disorder have no significant correlations with the scores of HAMD, HAMA （ P 〉 0.05 ）. Conclusion Functional lesion of autonomic nerve symptoms of depression may not be reflected by SSR sensitively,thus the value of clinical applications couldn＇t be confirmed.
出处
《四川精神卫生》
2013年第1期6-9,共4页
Sichuan Mental Health
关键词
抑郁症
交感神经皮肤反应
自主神经
Depressive disorder Sympathetic skin reaction Autonomic nerve
