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长程双联抗血小板治疗对国产雷帕霉素洗脱支架植入术后患者主要心血管不良事件的影响 被引量:4

Effects of Long-term Dual Antiplatelet Therapy on Domestic Produced Rapamycin Eluting Stent Implantation in Patients with Major Adverse Cardiovascular Events
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摘要 目的探讨长程双联抗血小板治疗对国产雷帕霉素洗脱支架(Firebird支架)置入术后冠心病患者心血管不良事件发生率的影响。方法纳入2004—2009年在柳州市人民医院植入Firebird支架的患者1107例,将其按照双联抗血小板治疗时间分为A、B两组,记录两组患者一般情况及临床随访结果,实际随访例数为1059例(共植入支架1431枚)。结果 (1)两组患者主要心血管不良事件发生率分别为5.5%、3.6%,两组间比较,差异无统计学意义(P>0.05)。(2)术后两组心绞痛发生率比较,差异有统计学意义(P<0.05)。(3)两组患者出血发生率比较,差异无统计学意义(P>0.05)。结论 Firebird支架植入术后延长双联抗血小板治疗时间至12个月以上更有利于降低心绞痛的发生,可进一步提高患者的生存质量。 Objective To discuss on longer dual antiplatelet therapy of domestic sirolimus -eluting stent (Firebird stent) implantation in patients with coronary heart disease after cardiovascular adverse events rate influence. Methods In 2004--2009 in 1107 cases of patients in Liuzhou City People's Hospital of implantation of Firebird stent, according to dual antiplatelet therapy time is divided into A, B two groups, recorded in two groups of patients and clinical follow - up results of actual follow - up, 1059 cases ( 1431 stents were implanted). Results ( 1 ) Two groups of patients with major adverse cardiovascular events were 5.5%, 3.6%, the comparison between two groups, the difference was not statistically significant (P 〉0. 05). (2) Occurred in two groups of angina pectoris after rate comparison, statistically significant differences (P 〈 0. 05). (3) Two groups of patients with bleeding rate comparison, no significant difference ( P 〉 0. 05 ). Conclusion Firebird stent implantation after prolonged dual antiplatelet therapy for more than 12 months time to help reduce the incidence of angina pectoris, can further improve the quality of life of patients.
出处 《实用心脑肺血管病杂志》 2013年第3期23-25,共3页 Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
基金 广西卫生厅自筹基金项目(Z2008409)
关键词 药物洗脱支架 阿司匹林 氯吡格雷 心血管不良事件 Drug - eluting stent Aspirin Clopidogrel Adverse cardiac events
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