摘要
目的比较两种皮肤保护剂在预防乳腺癌术后放疗急性放射性皮肤损伤的效果。方法 92例乳腺癌术后患者按编号的单双号分成观察组和对照组各46例。从第一天放疗开始使用皮肤保护剂(观察组采用伤口愈合凝胶,对照组采用放射治疗皮肤防护剂),每天2～3次,直至放疗结束。观察两组放疗急性放射性皮肤损伤的预防效果。结果观察组和对照组放射性皮肤损伤发生率分别为73.9%(34/46)和87.0%(40/46),差异无统计学意义(χ2=2.486,P>0.05);2级以上皮肤损伤发生率分别为13.0%(6/46)和32.6%(15/46),差异有统计学意义(χ2=4.998,P<0.05)。两组放射性皮肤损伤程度比较差异有统计学意义(u=0.951,P<0.05)。两组均无皮肤保护剂过敏而停用药物者。结论伤口愈合凝胶在预防乳腺癌术后放疗急性放射性皮肤损伤方面优于放射治疗皮肤防护剂,效果明显。
Objective To compare the effectiveness of two kinds of skin protecting agent for the prevention of acute radioactive skin reaction induced by radiotherapy after breast cancer operation. Methods 92 patients with breast cancer were divided randomly in- to observation group（46 cases using Flamigel）and contrast group（46 cases using Lifuning）. Skin protecting agents were for every pa- tient with breast cancer received radiotherapy from the first to the end of radiotherapy,2-3 times a day. Results The oecurence rate of skin radiation damage in the observation group and the contrast group is respectively 73.9% and 87% ,the difference was not statisti- cally significant （X2 = 2. 486, P = 0. 115, P 〉 0.05 ）. The occurence rate of 2 above the level of skin radiation damage in the observation group and the contrast group is respectively 13. 0% and 32. 6% ,the difference was statistically significant（x2 =4. 998 ,P = O. 025 ,P 〈 O. 05 ）. The skin radiation damage in observation group was significantly lower than that in contrast group（ P = 0. 029 ,P 〈 0. 05 ）. Con- clusions Flamigel is superior to Lifuning in the prevention of acute radioactive skin damage, and has obvious curative effect.
出处
《实用医院临床杂志》
2013年第2期96-97,共2页
Practical Journal of Clinical Medicine
关键词
乳腺癌
放射治疗
皮肤保护剂
预防
皮肤损伤
Breast cancer
Radiotherapy
Skin protecting agent
Prevention
Skin damage
