摘要
目的 探讨 5 Fu合并抗生素泰能区域动脉灌注 (regionalarterialinfusion ,RAI)能否降低急性坏死性胰腺炎 (ANP)感染和死亡率。方法 选择ANP 5 3例 ,分为A、B、C组。A组 16例 ,静脉途径给予 5 Fu及泰能 ;B组 2 2例 ,RAI途径给予 5 Fu ,静脉给予泰能 ;C组 15例 ,RAI途径交替使用 5 Fu和泰能。结果 C组感染率 (0 )明显低于A组(5 0 .0 % )和B组 (2 7.3 % ) ,P <0 .0 0 1,P <0 .0 1;B、C两组死亡率分别为 18.2 %和 13 .3 % ,均明显低于A组 (43 .8% ) ,P <0 .0 5。结论 RAI途径应用 5 Fu合并泰能能有效降低ANP感染及死亡率。
Objective To determine whether regional arterial infusion (RAI) of 5-Fu and imipenem could decrease infection and mortality of acute necrotic pancreatitis (ANP) or not. Methods Fifty three patients with ANP were devided into three groups, group A, 16 patients who received intravenous 5-Fu and imipenem, group B, 22 patients who received 5-Fu by RAI and imipenem intravenously, and group C, 15 patients who received both 5-Fu and imipenem by RAI. Results The incidence of infection of ANP in group C (0%) was significantly lower than that in group A (50.0%) and B (27.2%), and the mortality rates in group B (18.1%) and C (13.3%) were significantly reduced as compared with group C (43.8%). Conclusion RAI of 5-Fu and imipenem was effective in reducing ANP infection and mortality rates.
出处
《中国普外基础与临床杂志》
CAS
2000年第6期373-374,共2页
Chinese Journal of Bases and Clinics In General Surgery
关键词
急性坏死性胰腺炎
抗生素
胰酶抑制剂
区域性动脉灌注
Acute necrotic pancreatitis
Antibiotic
Protease inhibitor
Regional arterial infusion
