摘要
目的探讨不同时机治疗对妊娠合并梅毒患者妊娠结局及胎儿预后的影响。方法选取2006年6月-2011年6月在本院诊治的85例妊娠梅毒患者为研究对象,按治疗时间的不同将其分为A组(≤12周治疗组)、B组(13～28周治疗组)及C组(>29周治疗组),对三组患者的妊娠结局、新生儿预后情况、Apgar评分及母婴RPR滴度进行比较。结果 A组的足月分娩率为93.55%,高于B组(67.86%)和C组(50.00%),差异有统计学意义(P<0.05);A组不良妊娠结局发生率为6.50%,明显低于B组(32.14%)及C组(50.00%),差异有统计学意义(P<0.05)。A组的新生儿预后情况最好,新生儿梅毒的发生率为0,低于B组(26.09%)和C组(45.00%),差异有统计学意义(P<0.05)。A组新生儿的1min及5minApgar评分优于B组和C组,差异有统计学意义(P均<0.05)。A组的母婴RPR滴度也最佳(P<0.05)。结论早期治疗对于改善妊娠梅毒患者的妊娠结局及胎儿的预后有着重要意义。
Objective To investigate of different curative opportunities on the pregnancy and prognosis of pregnant syphilis. Methods The total of 85 patients with pregnant syphilis from 2006 to 2011, were divided into three groups： group A（ ≤12 gestational weeks, 31 cases） ,group B（from 13 to 28 gestational weeks,28 cases） , group C （≥29 gestational weeks,26 cases）. All the patients received certain treatment. The pregnancy outcome, prognosis, Apgar scores and titers of RPR in mothers and infants were detected and a comparison was made among the 3 groups. Results The term delivery rate of group A was 93.55% , which was higher than those in group B and group C （ P 〈 0. 05 ）. The incidences of babies with congenital syphilis and harmful effects in group A were lower than those in group B and group C （ P 〈 0. 05 ）. Group A was superior in the 1st min and 5th min Apgar scores to those in group B and group C（P 〈0. 05）. The detection results of the titers of RPR of mothers and infants in group A were good （ P 〈 0. 05 ）. Conclusion Early treatment has a positive effect on the prognosis of the patients with pregnant syphilis.
出处
《中国皮肤性病学杂志》
CAS
北大核心
2013年第3期274-276,共3页
The Chinese Journal of Dermatovenereology
关键词
治疗时机
妊娠梅毒
影响
预后
胎儿
新生儿
Curative opportunity
Pregnant syphilis
Effect
Prognosis
Fetus
Neonate
