摘要
目的:观察奥美拉唑和必可酮气雾剂联合治疗儿童胃食管反流性哮喘的疗效.方法:分别给予84例胃食管反流性哮喘患儿口服质子泵抑制剂奥美拉唑,每次0.3-0.4mg/kg,2次/d,同时常规吸入皮质激素必可酮气雾剂,3次/d,每次吸入100μg,持续2wk后改为50μg,持续治疗3mo后复查并进行评分.结果:胃食管反流症和支气管哮喘在治疗前、后症状评分别为:胃食管反流症状评分:治疗前3.9分±1.0分、治疗后1.6分±0.7分;支气管哮喘症状评分:治疗前4.2分±1.0分、治疗后2.4分±0.8分,差异有统计学意义(P<0.05,0.01).结论:应用奥美拉唑和必可酮气雾剂联合治疗小儿胃食管反流性哮喘具有显著疗效,且耐受性良好.
To observe the etficacy ot omeprazole in combination with becotide spray in the management of gastroesophageal reflux asthma in children. METHODS： Eighty-four children with gastro esophageal reflux asthma were given omeprazole （0.3-0.4 mg/kg） by oral administration, twice per day, and becotide spray （100 ug, 50 ug after 2 wk） by inhalation, three times per day. The therapy lasted 3 mo, and the symptoms were scored before and after treatment. RESULTS： The pre-treatment and post-treatment scores of gastroesophageal reflux were 3.9 ± 1.0 and 1.6 ±0.7, and the scores of asthma were 4.2 ± 1.0 and 2.4 ± 0.8. There were significant differences between before and after therapy inscores of gastroesophageal reflux and asthma （P 〈 0.05, 0.01）.
出处
《世界华人消化杂志》
CAS
北大核心
2013年第5期445-447,共3页
World Chinese Journal of Digestology
