摘要
对临床分离的68株铜绿假单胞菌的临床分布及耐药性进行回顾性分析。68株铜绿假单胞菌主要分布于ICU病房,占35.29%,其次为呼吸内科、烧伤科、心血管内科、血液科、普外科和骨科,分别占25.00%(17株)、16.18%(11株)、7.35%(5株)、5.88%(4株)、5.80%(4株)和4.41%(3株)。铜绿假单胞菌对氨苄西林耐药率最高,为95.59%,其次对头孢替坦、磺胺甲噁唑/甲氧苄啶、头孢唑啉、头孢曲松的耐药率也较高,分别达92.65%、91.18%、89.71%和85.29%;对哌拉西林/他唑巴坦、左氧氟沙星、亚胺培南、庆大霉素、妥布霉素和阿米卡星的耐药率均在30%以下。铜绿假单胞杆菌临床分布广泛,耐药严重,应避免临床抗菌药物的滥用。
The clinical distribution and drug sensitivity of 68 Pseudomonas aeruginosa isolates were analyzed retrospec tively. Sixty-eight P. aeruginosa isolates were mainly from the ICU （35.29%）, followed by Respiratory medicine （25. 00%, 17 strains）, Burn units （16. 18 %, 11 strains）, Cardiovascular medicine （7. 35 %, 5 strains）, Hematology （ 5. 88%, 4 strains）, General surgery （5.80/00, 4 strains）and Orthopedics （4.41%, 3 strains）. P. aeruginosa had resistance to ampicillin of up to 95. 59%, followed by resistance to cefotetan of 92. 65%, resistance to sulfamethoxazole/trime- thoprim of 91.18%, resistance to cefazolin of 89.71%, and resistance to ceftriaxone of 85. 29%. Its resistance to pip eracillin/tazobactam, levofloxacin, imipenem, gentamicin, tobramyein, and amikacin was less than 30%. P. aeruginosa has a widespread clinical distribution and is highly resistant. The misuse of antimicrobials should be avoided.
出处
《中国病原生物学杂志》
CSCD
北大核心
2013年第1期I0004-I0004,F0003,共2页
Journal of Pathogen Biology
关键词
铜绿假单胞菌
临床分布
耐药性
Pseudomonas aeruginosa
clinical distribution
drug resistance
