摘要
目的:优选砂烫马钱子的炮制工艺参数,以有效控制马钱子质量。方法:采用正交试验法,以马钱子碱、士的宁含量为指标,评价油砂粒度、砂料比、炒制温度、炒制时间对马钱子质量的影响。结果:最佳炮制工艺为中砂(300～600μm),砂料比7∶1,炒制温度(190±5)℃,炒制时间4 min。结论:优选的炮制工艺稳定可行,适用于大规模生产。
Objective：To optimize processing technology parameters of Strychnos nux-vomica heated with sand,in order to control quality of S. nux-vomica effectively. Method： With the content of brucine and strychnine as indexes,orthogonal test was used to evaluate effect of oil-sand degree,sand-material ratio,frying temperature and time on processing technology parameters of S. nux-vomica. Result： Optimum processing technology parameters were as followings：medium sand （300-600 μm）,sand-material ratio 7∶1,frying temperature （190±5） ℃,frying time 4 min. Conclusion： Optimized processing technology was suitable and feasible,it was suitable for mass production.
出处
《中国实验方剂学杂志》
CAS
北大核心
2013年第5期25-28,共4页
Chinese Journal of Experimental Traditional Medical Formulae
基金
中医药行业科研专项(201107008)
关键词
马钱子
砂烫法
正交试验
炮制工艺
Strychnos nux-vomica
heated with sand
orthogonal test
processing technology
