摘要
本实验结果显示,大鼠耗竭游泳时,心肌和股四头肌线粒体脂质过氧化水平升高,心磷脂含量下降,并同时测定到细胞色素C氧化酶活性的降低。
The effects of exhaustive swimming on the mitochottdrial cytochrome C oxidase activity and cardi-
olipin content were investigated in rat myocardium and quadriceps. After exhaustive swimming, it was
found that cytochrome C oxidase activities for both myocardium mitochondria and quadriceps mitoch-
ondria as well as cardiolipin contents in the same tissues significantly decreased. The levels of lipid
peroxidation for both tissues mentioned above significantly elevated.
Based on the point of view of free radical biology and membrane lipid--membrane protein intera-
ction, these results suggest that reactive oxygen species may play an important role in mitochondrial
injury induced by exhaustive exercise.
出处
《北京医科大学学报》
CSCD
1991年第6期435-437,共3页
Journal of Peking University(Health Sciences)
基金
国家自然科学基金
关键词
线粒体
心磷脂
细胞色素C
氧化酶
Mitochondrion
Free radical
Cytochrome C oxidase
Cardiolipin
