摘要
作为避孕疫苗的生殖激素抗原主要有:GnRH、FSH、LH及hCG。这些抗原显示了不同程度的避孕效应,其中,hCG疫苗是唯一进入Ⅱ期临床试验的避孕疫苗;而且,GnRH及hCG疫苗在非避孕方面具有广阔的应用前景。
The molecules that being explored for contraceptive vaccine （CV） development mainly include reproductive hormones GnRH, FSH, LH and hCG. CV targeting the above-mentioned antigens has shown varieddegrees of contraceptive efficiency. The hCG vaccine is the first vaccine to undergo Phase I and Phase II clinical trials in humans. Moreover, both GnRH and hCG vaccines have an exciting application prospects in non-contraceptive fields.
出处
《免疫学杂志》
CAS
CSCD
北大核心
2013年第3期264-266,共3页
Immunological Journal
关键词
避孕疫苗
生殖激素
避孕
Contraceptive vaccine
Reproductive hormones
Birth control
