摘要
目的探讨腹型过敏性紫癜患儿的临床特征、胃镜特点及其与幽门螺杆菌的关系,为疾病早期诊断提供依据。方法回顾性分析460例腹型过敏性紫癜患儿的临床特征,以及其中69例行胃镜检查患儿的胃镜特点、122例幽门螺杆菌感染检测结果。结果患儿均有腹部疼痛,腹痛部位不固定,症状重而腹部体征较轻,腹痛发生1/2～45 d后皮肤出现紫癜。胃镜检查见胃肠黏膜充血、水肿、出血点、糜烂、溃疡,病变以胃窦、胃体、十二指肠降部及球部为主,但十二指肠黏膜改变最严重。采用黏膜尿素酶试验或免疫印迹法检测幽门螺杆菌阳性54例。结论腹型过敏性紫癜临床表现无特异性。胃及十二指肠黏膜类似皮肤紫癜样病变是其常见的镜下特点,有早期诊断价值。过敏性紫癜与幽门螺杆菌感染的关系有待进一步研究。
Objective To discuss the clinical features and endoscopic characteristics of abdominal type Henoch purpura in children and its relationship with Helicobacter pylori to provide the basis for early diagnosis. Methods Retrospective analysis of 460 cases of six years of Henoch purpura in children with abdominal clinical features, as well as 69 children affected by endoscopy and endoscopic charac- teristics of H. pylori infection in routine testing of 122 test results. Results All children experienced abdominal pain, the location was not fixed, and the symptoms were serious, but the signs were light. After the abdominal pain for 1/2 -45 days, the skin presented the pur- pura. Gastroseopic features included hyperemia and edema of gastrointestinal mucosa, hemorrhagic spots, erosion and ulceration, lesions mainly in the gastric antrum, body, descending duodenum and bulbar, but the duodenum mucous membrane changed in the most serious. Mucosal urease test or Western blot detection showed H. pylori-positive in 54 cases. Conclusion Abdominal type Henoch purpura pres- ented no specific clinical features. Similar skin purpura of the stomach and duodenum are common gastroscopic characteristic, which has value of early diagnosis. Kelationship of Henoeh purpura and H. pylori infection needs further study.
出处
《安徽医药》
CAS
2013年第2期234-236,共3页
Anhui Medical and Pharmaceutical Journal
关键词
过敏性紫癜
胃镜检查
胃肠道
幽门螺杆菌
儿童
purpura, schoenlein-henoch
gastroscopy
gastrointestinal tract
helicobacter pylori
child
