摘要
目的调查耐多药结核病(multidrug-resistant tuberculosis,MDR-TB)患者的抑郁状态与社会支持情况,并探讨二者之间的相关因素。方法采用1∶1配比对照研究,对94例MDR-TB患者及相同数量的对照(从MDR-TB户籍同区的人群中选取)使用Zung抑郁自评量表(SDS)、社会支持评定量表(SSRS)进行问卷调查。调查MDR-TB患者96例,发出问卷96份,回收有效问卷94份,有效率97.9%,将有效回答的94例患者全部纳入MDR-TB组。调查MDR-TB患者户籍同区的人群,发出问卷718份,回收有效问卷676份,有效率94.2%;从676例户籍同区的人群中按照与MDR-TB患者同性别、年龄相近(相差≤2岁)原则进行1∶1配对,选取94例纳入对照组。将两组调查的SDS与SSRS问卷进行统计,对所获得的数据资料进行处理,采用双变量相关分析、t检验及单因素方差分析,P<0.05为差异有统计学意义。结果 94例MDR-TB患者SDS得分为(52.80±8.34)分,高于对照组得分(41.81±10.26)分(t=8.284,P<0.01),45例MDR-TB患者存在抑郁状态;MDR-TB患者获得的社会支持总分为(35.65±5.47)分,少于对照组得分(41.80±6.62)分,差异有统计学意义(t=6.457,P<0.01);MDR-TB患者SDS得分与社会支持总分呈负相关(r=-0.520,P<0.01),即获得的社会支持得分越高,抑郁症状越轻。结论多数MDR-TB患者存在抑郁状态,应该重视社会支持系统,改善MDR-TB患者的抑郁状态,以提高其生活质量。
Objective To investigate the depression and social support status of multidrug-resistant tuberculosis（MDR-TB） patients,and to explore the correlation between the two factors.Methods Ninety-four MDR-TB patients in case group and 94 people selected from the same area of MDR-TB patients＇ household register in control group were investigated by Zung Self-Rating Depression Scale（SDS） and Social Support Rating Scale（SSRS）.Ninety-six questionnaires were issued for MDR-TB patients and 94 valid were returned with the effective response rate of 97.9%.All these 94 patients were enrolled in case group.718 questionnaires were issued for people selected from the same area of MDR-TB cases＇ household register and 676 valid were returned with the effective response rate of 94.2%.Among these 676 people,94 people were selected with the same gender and age（≤ 2 years＇ difference） of cases（1∶1 matched pair）.Bivariate correlation analysis,t-test and one-way analysis of variance were applied.Results The average SDS score of case group was（52.80±8.34）,which was higher than the control group（41.81±10.26）（t=8.284,P0.01）,45 patients were depressed;MDR-TB patients（35.65±5.47） received less support from the society than the control group（41.80±6.62）（t=6.457,P0.01）,the difference was statistically significant.The SDS score of MDR-TB patients was negatively correlated with the total score of social support（r=-0.520,P0.01）,which indicated the more social support the patients got,the less depressive symptoms they had.Conclusion Attention should be paid to the social support system and improvement of MDR-TB patients＇ depression in order to improve the quality of their lives.
出处
《中国防痨杂志》
CAS
2013年第2期142-145,共4页
Chinese Journal of Antituberculosis
关键词
结核
抗多种药物性
药物疗法
抑郁
社会支持
问卷调查
Tuberculosis
multidrug-resistant/drug therapy
Depression
Social support
Questionnaires
