摘要
卒中后抑郁(post-stroke depression,PSD)是卒中后的常见并发症,不仅影响卒中患者的精神和神经功能恢复,甚至会增加惠者的致残率和死亡率。常规影像学在PSD的相关解剖学部位与边缘系统-前额叶皮层-纹状体-苍白球-丘脑神经解剖环路假说的确立和巩固方面具有重要作用,但并不能对PSD进行早期的预测,功能磁共振在PSD的早期识别上具有优势,为PSD的研究提供了支持。
Post-stroke depression(PSD) is a common complication of cerebrovascular disease, which may impede neurological rehabilitation of patients with PSD, even kill more patients suffering from stroke. Reports on the incidence of PSD vary from each other greatly; it is concentrated between 20% and 50%. Although regular imaging plays a significant role on the foundation and supports the hypothesis of limbic-cortical-striatal-pallidal-thalamic(LCSPT) circuit, it still cannot serves good to early identify of PSD compared with functional magnetic resonance imaging(MRI). Hence, functional MRI would lay the foundation and promote early identification and prevention of PSD on the basis of nowadays survey on depression,
出处
《中国卒中杂志》
2013年第2期142-146,共5页
Chinese Journal of Stroke
基金
首都医学发展科研基金资助项目(2009-3105)
北京市自然科学基金(7102050)
关键词
抑郁
卒中
磁共振成像
Depression
Stroke
Magnetic resonance imaging