摘要
目的:对836例隐性梅毒病例进行分析,为完善针对隐性梅毒诊断的标准提供依据。方法:收集江苏省6个国家级性病区域监测点2008～2010年诊断的隐性梅毒病例相关资料,并收集这些病例的血清,开展非梅毒螺旋体抗原血清学(TRUST)和梅毒螺旋体抗原血清学试验(ELISA)的复核。结果:836例隐性梅毒病例平均年龄为(42.65±13.26)岁,87.92%(735/836)诊断病例来源于综合性医疗机构,82.66%(691/836)病例由住院和术(输血)前筛查检出,55.86%(467/836)的病例首选青霉素药物治疗,ELISA和TRUST同时阳性者占92.35%(772/836),TRUST阳性且滴度>1∶8的为27.28%(212/777)。结论:要提高非性病诊疗机构人员隐性梅毒的实验室诊断能力和临床治疗的规范性,为实现《中国预防与控制梅毒规划(2010-2020年)》的目标奠定基础。
Objective：To improve the latent syphilis diagnostic criterion through investigating 836 cases of latent syphilis.Methods：Collecting the data of 836 cases of latent syphilis in 6 national sexually transmitted diseases（STD） sentinel surveillance in Jiangsu province from 2008 to 2010,moreover,the serums of the cases were collected to check the diagnostic veracity with non treponemal antigen serological test（TRUST） and treponemal antigen serological test（ELISA）.Results：The average age of 836 cases latent syphilis was（42.65 ± 13.26） years old;87.92% cases of the latent syphilis were came from comprehensive medical institutions;82.66% cases were checked out with to be hospitalized;55.86% cases were firstly treated with penicillin;92.35% cases were ELISA and TRUST positives simultaneously and 27.28% cases of TRUST titer were more than 1∶8.Conclusion：In order to attain the aims of prevention and control of syphilis in planning of China（2010-2020）,the diagnosis and therapy abilities of latent syphilis must be improved.
出处
《南京医科大学学报（自然科学版）》
CAS
CSCD
北大核心
2012年第12期1781-1783,共3页
Journal of Nanjing Medical University(Natural Sciences)
基金
江苏省自然科学基金(BK2009435)
江苏省医学重点人才项目(RC2011086
RC2011087)
江苏省预防医学课题(Y201029)
关键词
梅毒
隐性梅毒
性病
调查分析
syphilis
latent syphilis
sexually transmitted diseases（STD）
investigation
