摘要
目的探讨原发性IgA肾病（IgAN）临床与病理的相关性。方法对158例原发性IgAN患者肾活检后分析其病理分型和临床表现。结果IgAN患者临床表现与病理呈不一致性，IgAN患者尿蛋白量多寡与病理分型相关。无症状尿检异常型（V-ab）尿蛋白量多少变化悬殊，肾间质损害呈慢性化改变者，尿蛋白量并无明显增多。高血压型（HT）比较其他临床分类其病理损伤较重。结论IgAN患者临床表现与病理呈不一致性，肾活检是判断预后的重要方法。
Objective To investigate the relationship between clinical features and pathologic results of primary IgA nephropathy（IgAN）.Methods The clinical features and pathologic results of 158 IgAN patients diagnosed by renal biopsy were recorded.Results The clinical features were inconsistent with pathologic results.The quantity of proteinuria was positively associated with the severity of pathologic results.The extent of proteinuria of asymptomatic IgAN subjects varied widely.The quantity of proteinuria between subjects with chronic interstitial injury and those not had no significant difference.Subjects with hypertension showed more severe pathologic injury than subjects without hypertension.Conclusion The clinical features were inconsistent with pathologic results,and the renal biopsy is one of the important methods to decide the feature of diseases.
出处
《中国血液流变学杂志》
CAS
2012年第4期600-601,641,共3页
Chinese Journal of Hemorheology
关键词
IGA肾病
临床分型
肾病理指标
IgA nephropathy
clinical feature
pathologic results of nephropathy
