摘要
目的:比较不同的针刺方法对人脑功能的调节作用。方法:16名健康成年被试(男8例),每名被试均参加4次实验,分别接受手针、电针、经皮穴位电刺激及触觉对照刺激,在刺激过程中同时进行功能性磁共振(血氧依赖水平,blood oxygen level dependent,BOLD)数据采集。结果:4种刺激均表现为对躯体运动感觉系统、岛叶和小脑的BOLD信号激活。此外,电针还表现为对边缘系统的BOLD信号的抑制,而经皮穴位电刺激则特异性地激活了基底核(P<0.001,uncorrected,k>22)。结论:电针和经皮穴位电刺激可模拟手针对脑BOLD信号的调节作用,表明3者有其共性,又各具特色。其生理意义有待进一步阐明。
Objective： To explore the effects of manual acupuncture （MA）, electroacupuncture （EA） and transcutaneous electrical acupoint stimulation （TEAS） on the human brain activity, expressed by BOLD signal changes in functional magnetic resonance imaging （fMRI）. Methods： 16 （8 male） healthy right- handed subjects were recruited to participate in four fMRI scanning sessions, and in each session received only one kind of stimulation, including MA, EA, TEAS and skin touch control. Data processing was carried out by using the Statistical Parametic Mapping （SPM8）. Results： EA, MA and TEAS, all three kinds of stimulation produced fMRI signal increase in the primary somatic sensory area （S I ）, secondary somatic sensory area （S ][ ）, insula and cerebellum. EA produced significant signal decrease in limbic structures including hippocampus and parahippocampal gyrus, while TEAS specifically produced fMRI signal increase in putamen and claustrum （P 〈 0.001, uncorrected, number of voxel 〉 22）. Conclusion： Different forms of acupuncture produced common effects on the human brain BOLD signal expression, with some characteristic changes. The functional impacts of these changes deserve further investigation.
出处
《中国疼痛医学杂志》
CAS
CSCD
北大核心
2013年第2期75-79,共5页
Chinese Journal of Pain Medicine
基金
国家重点基础研究发展计划(973)项目(2013CB531905)资助
关键词
电针
手针
经皮穴位电刺激
功能性磁共振
Manual acupuncture
Electroacupuncture
Transcutaneous electrical acupoint stimulation
Functional magnetic resonance imaging
