摘要
目的分析经阴道超声测量宫颈长度联合血清松弛素水平检测对早产的预测效能。方法选取单胎初产孕妇280例，于孕中、晚期经阴道超声测量宫颈长度，孕中、晚期及产后测量血清松弛素水平。分析宫颈长度、血清松弛素水平单独预测和宫颈长度与血清松弛素水平联合预测早产的敏感度等。结果孕中期宫颈长度及血清松弛素水平预测早产的敏感度分别为54．43％和57．72％，孕晚期敏感度分别为62．74％和66．49％，孕晚期的预测效能较孕中期理想。而宫颈长度联合血清松弛素水平预测早产的敏感度在孕中期为70．76％，孕晚期为71．51％，明显优于两种方法单独预测时的敏感度，差异有统计学意义（P〈0．05）。结论宫颈长度联合血清松弛素水平预测早产可显著提高预测的敏感度，对尽早发现早产风险及尽早干预具有重要作用。
Objective To determine the efficiency of cervical length by transvaginal sonography combined with serum relaxin for predicting premature birth. Methods The study enrolled 280 single births primipara. Cervical length was measured by transvaginal sonography during mid-trimester and late-trimester of pregnancy. Serum relaxin was measured during mid-trimester of pregnancy,late-trimester of pregnancy and postpartum. Sensitivity of cervical length, serum relaxin and cervical length combined with serum relaxin were applied for predicting premature birth. Results The sensitivity of cervical length and serum relaxin during mid-trimester of pregnancy for predicting premature birth were 54.43% and 57.72% ,respectively. The sensitivity of cervical length and serum relaxin during late-trimester of pregnancy for predicting premature birth was 62.74% and 66.49% ,respectively. Sensitivity of cervical length and serum relaxin during late-trimester of pregnancy for predicting preterm birth were more satisfying than those during mid-trimester of pregnancy. The sensitivity of cervical length combined with serum relaxin for predicting premature birth were 70.76% and 71.51% ,which were obviously higher than those obtained using cervical length or serum relaxin alone. Conchlsion The combination of cervical length and serum relaxin can significantly improve the sensitivity of predicting premature birth, which can diagnose premature birth early and exactly.
出处
《中国医师进修杂志》
2013年第3期27-29,共3页
Chinese Journal of Postgraduates of Medicine
关键词
子宫颈
松弛素
早产
预测
Cervix uteri
Relaxin
Premature birth
Forecasting
