摘要
目的观察静脉滴注硝酸甘油联合口服赖诺普利治疗顽固性心力衰竭的疗效。方法 46例符合标准的患者入选本研究。随机分为两组,治疗组在常规抗心力衰竭治疗的基础上加用静脉滴注硝酸甘油与口服赖诺普利;对照组给予常规抗心力衰竭治疗,疗程7～10d。观察两组的治疗效果。结果治疗组显效率为47.8%(11/23),总有效率为86.9%(20/23)。对照组显效率为30.4%(7/23),总有效率为69.6%(16/23)。治疗后两组疗效对比,显效率差异有统计学意义(P<0.05),总有效率差异有统计学意义(P<0.05)。结论静脉滴注硝酸甘油联合口服赖诺普利治疗顽固性心力衰竭疗效显著,用药安全,不良反应少。
Objective To observe the clinical effects of nitroglycerin intervenous drop infusion combined with lisinopril oral use in treatment of intractable heart failure. Methods Forty-six patients selected in accordance with our standards were chosen into research and were randomly divided into two groups. Patients in the treatment group were given nitroglycerin intervenous drop infusion combined with lisinopril oral use in addition to regular treatment of intractable heart failure while patients in the control group were given regular treatment of intractable heart failure. The course of treatment was 7 to 10 days. Clinical effects were observed and compared. Results Excellence rate in the treatment group was 47.8% （11/23）, the total effective rate was 86.9% （20/23）. Excellence rate in the control group was 30.4% （7/23）, the total effective rate was 69.6% （16/23）. Statistically significant differences existed in excellence and total effective rate between two goups （P 〈 0.05）. Conclusion Nitroglycerin intervenous drop infusion combined with lisinoprit oral use in treatment of intractable heart failure has outstanding clinical effects with drug safety and little adverse effects.
出处
《中国当代医药》
2013年第6期79-80,82,共3页
China Modern Medicine
