摘要
目的:探讨糖尿病肾病早期诊断中尿微量蛋白和Ⅳ型胶原蛋白检测的应用研究。方法:06例患者均为我院收治糖尿病肾病患者,为我院2011年1月-2012年5月间患者,定为糖尿病组,选择同期健康体检者106例定为对照组,检查两组患者尿微量蛋白、Ⅳ型胶原蛋白,及RBP/Cr、TRF/Cr、IgG、Alb、α1-MG、β2-MG。结果:两组研究对象IV-C、mAlb/Cr、RBP/Cr、TRF/Cr、IgG、Alb、α1-MG、β2-MG对比,均存在显著差异,且糖尿病组明显高于正常组,P<0.05。结论:尿Ⅳ-C、尿微量蛋白均可以测定是否有糖尿病肾病,但尿Ⅳ-C出现相对要比尿微量蛋白要早,可更早预测是否出现糖尿病肾病发生。
Objective：To investigate the application of diabetic nephropathy urinary microalbumin and type IV collagen on early diagnosis.Methods：106 patients were admitted to our hospital for diabetic nephropathy patients in our hospital in,January 2011 to may 2012,scheduled for the diabetic group,the 106 healthy persons were selected as control group at same period,the urinary protein,collagen type IV,and RBP/Cr,TRF/Cr,IgG,Alb,α 1-MG,β2-MG of two groups of patients were examined.Results：The IV-C,mAlb/Cr,RBP/Cr,TRF/Cr,IgG,Alb,α1-MG,β2-MG of two group were compared,there were significant differences,and the diabetic nephropathy group was significantly higher than that in normal group,P0.05.Conclusion：UrinaryⅣ-C,urine trace proteins can determine whether diabetic nephropathy,but urinaryⅣ-C appears relatively more early than trace protein in urine,can predict whether earlier diabetic nephropathy r appear.
出处
《中国医药导刊》
2012年第12期2147-2148,共2页
Chinese Journal of Medicinal Guide
