摘要
目的:探讨银杏达莫注射液治疗早期糖尿病肾病的临床疗效。方法:回顾性分析我院于2010年7月至2012年1月收治的80例早期糖尿病肾病患者的临床资料,按随机数表法将其分为对照组和观察组,每组各40例,其中对照组给予常规药物治疗试验组行银杏达莫注射液治疗。进行1-2个月的随访,对比两组患者的临床疗效和血尿素氮(BUN)及血清肌酐(Scr)的生化指标变化。结果:两组内相比,治疗后所有患者的生化指标变化均优于治疗前(P<0.05);而两组间相比,实验组患者的总有效率为95.0%,高于对照组的82.5%,有统计学差异(P<0.05),且肾功能指标变化亦优于对照组(P<0.05)。结论:运用银杏达莫注射液治疗早期糖尿病肾病,临床效果显著,能够延缓肾功能恶化,并通过一系列生理作用,改善患者的生活质量,对糖尿病肾病起到有效地治疗和保护作用。
Objective：To investigate the method and effect of Yinxingdamo injection in the comprehensive efficacy of early diabetic nephropathy.Methods：The clinical data of 80 cases admitted to our hospital from July 2010 to January 2012 with early diabetic nephropathy were analyzed retrospectively.They were divided into control group of 40 cases and observation group with 40 cases in accordance with the admission time.The control group was taken with conventional drug therapy,and the experimental group was taken with Yinxingdamo injection therapy.1-2 months of follow-up,biochemical indexes of the two groups and h clinical efficacy and blood urea nitrogen（BUN） and serum creatinine（Scr） were compared in the two groups.Results：Compared within the two groups after treatment,all patients with biochemical indicators of change were better than before treatment（P0.05）.Compared between the two groups,the total effective rate of the experimental group was 95.0%,higher than the control group of 82.5%,with a significant difference（P0.05）.And the biochemical indicators of change was better than the control group（P0.05）.Conclusion：The use of Ginkgo biloba extract and dipyridamole injection treatment of early diabetic nephropathy has a significant clinical effect,can delay the deterioration of renal function,and improve patientsapos;quality of life by a series of physiological effects,play an effective role in the treatment and protection of diabetic nephropathy.
出处
《中国医药导刊》
2012年第12期2140-2141,共2页
Chinese Journal of Medicinal Guide
关键词
银杏达莫
糖尿病肾病
血尿素氮
血清肌酐
Yinxingdamo
Diabetic nephropathy
Blood urea nitrogen
Serum creatinine
