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从临床优势看DPP-4抑制剂替代磺脲类药物的可能性 被引量:1

Apromising future of replacing sulponylureas with DPP-4 inhibitors based on an analysis of clinical studies
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摘要 磺脲类药物应用于临床治疗糖尿病已有五十多年的历史,其降糖效果肯定,价格低廉,在2型糖尿病的治疗中占有重要地位。但其存在低血糖风险大、增加体重、易继发性失效等缺点,限制了它在临床的应用。近几年来新上市的降糖药物DPP-4抑制剂则表现出降糖效果良好、低血糖风险小、不增加体重、效果持久等优势。越来越多的国内外指南将DPP-4抑制剂推荐为糖尿病治疗的二线用药,体现出替代磺脲类药物的趋势。
出处 《药品评价》 CAS 2012年第34期41-43,共3页 Drug Evaluation
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