摘要
患者男,83岁。左侧腋窝红斑伴瘙痒6年。多次按湿疹治疗,无效;3年前始皮损伴轻度疼痛,瘙痒明显,反复破溃不能愈合。近日来皮损增大明显,予手术切除。切除物组织病理示:表皮轻度角化过度,表皮全层可见单个或成巢的Paget细胞,真皮浅层较多淋巴细胞浸润;AB染色(+),PAS染色(-);免疫组化示:CK7,CK8/18,CEA和Ki67均(+);S100和HMB45均(-)。诊断:乳房外Paget病。
A 83-year-old male, complaining of itch, had been suffered with erythema on the axillary fossa for 6 years, re- peatedly misdiagnosed as eczema and received the Symptomatic treatment,but the symptom did not get bet- ter. He felt a little pain and much itch on the erythema with the skin disunion 3 years ago. The extent of the erythema got bigger recently and he received resection at last. Histological examnation showed： Epidermis hyperkeratosis, single or a nest of Paget cells in the epidermis and part of eccrine ductal epithelium, multiple lymphocytic infiltration in the superficial layer of dermis; AB staining（ ＋ ） ,PAS staining（ - ）. Immunohis- tochemistry showed ： CK7, CK8/18, CEA and Ki67 （ ＋ ） , S 100 and HMB45 （ - ）. Diagnosis ： extramammary Paget＇ s disease.
出处
《中国皮肤性病学杂志》
CAS
北大核心
2013年第2期181-182,184,共3页
The Chinese Journal of Dermatovenereology
关键词
PAGET病
乳腺外
腋窝
Paget＇ s disease
Extra mammary
Axilla
