摘要
糖尿病血管病变是糖尿病的一个最常见的慢性并发症,可累及全身的大血管及微血管,其中大血管病变导致的心脑血管疾病是2型糖尿病患者首要的死亡原因,约占2型糖尿病死因的50%。糖尿病合并大血管病变是目前糖尿病并发症研究的热点,但其具体机制至今尚未完全阐述清楚。本文综述了高胰岛素血症与动脉粥样硬化研究现状与进展,并探讨其引发动脉粥样硬化的可能机制。
Vascular disease is one of the common complications of diabetes mellitus including macrovascular disease and microvascular disease. Macrovascular disease （ commonly refers to atherosclerosis） which leads to cardiac-cerebral vascular disease is a major cause of death in patients with type 2 diabetes mellitus. Although diabetic macrovascular disease has become one of hot research in the diabetic complications field, the underlying mechanism is still far from being completely elucidated. This review describes current situation and prospect concerning hyperinsulinemia and atherosclerosis and discusses the possible pathogenesis.
出处
《中国动脉硬化杂志》
CAS
CSCD
北大核心
2013年第1期79-83,共5页
Chinese Journal of Arteriosclerosis
基金
国家自然科学基金青年项目(30900707)
