摘要
目的探讨树突状细胞与细胞因子诱导的杀伤细胞(DC/CIK细胞)治疗的副反应。方法回顾性分析152例接受DC/CIK细胞治疗的癌症患者的临床资料。结果 152例患者中,肝功能异常13例,发生率为8.6%。肾功能异常12例,发生率为7.9%。心电图异常15例,发生率为9.9%。贫血8例,发生率为5.3%。发热16例,发生率为10.5%。无治疗相关性死亡。结论 DC/CIK细胞治疗可引起轻度副反应。但是,如果不给予高度重视,早期发现,早期处理,则可能导致严重后果。
Objective To explore the side effects of dendritic cells and cell factors induced the killer cell (DC/CIK cells) treatment. Methods The clinical data of 152 cases of cancer patients receiving DC/CIK cell therapy were retrospectively analyzed. Results In the 152 patients, there were 13 cases of abnormal liver function, the rate of 8.6%. 12 cases of renal dysfunction, the rate of 7.9%. 15 cases of ECG abnormalities, the rate of 9.9%. 8 cases of anemia, the rate of 5.3% and 16 cases of fever, the rate of 10.5%. There was not treatment-related death. Conclusion DC/CIK cell therapy can cause mild side effects. However, if you do not attach great importance to early detection and early treatment, it may lead to serious consequences.
出处
《中国当代医药》
2013年第1期6-8,共3页
China Modern Medicine
基金
吴阶平医学基金会临床科研专项资助基金(编号:320.6799.1096)