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补肾活血调周法改善反复体外受精-胚胎移植失败患者子宫内膜容受性临床观察 被引量:21

Clinical Observation on Endometrial Receptivity of Patients with Failure IVF-ET Treated with Method for Invigorating Kidney and Activating Blood And Regulating Menstruation
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摘要 目的:观察补肾活血调周法改善子宫内膜容受性的临床疗效,并探讨其作用机理。方法:将60例反复IVF-ET失败患者随机分为中药+控制性超排组(实验组,30例)和控制性超排组(对照组,30例),观察治疗前后及两组之间的子宫内膜厚度、类型及血流状态。结果:(1)实验组患者治疗后子宫内膜厚度增加明显,差异有统计学意义(P<0.05);(2)实验组患者治疗后A型+B型内膜的数量增加,但差异无统计学意义(P>0.05);(3)实验组患者治疗后子宫内膜阻力指数明显低于治疗前,差异有统计学意义(P<0.05),子宫内膜穿支血流改善,差异有统计学意义(P<0.05);(4)试验组和对照组比较,在子宫内膜厚度,内膜阻力指数,子宫内膜穿支血流3项指标上均有差异,并且差异有统计学意义(P<0.05);(5)实验组种植成功率高于对照组,差异有统计学意义(P<0.05)。结论:补肾活血调周法能改善子宫内膜厚度,改善子宫内膜血流,可以提高子宫内膜容受性,从而有助于着床,提高体外授精-胚胎移植成功率。 Objective:The study is to observe the methods for invigorating kidney and activating blood and regulating menstruation on endometrial receptivity of patients with failure IVF-ET and its mechanism will also be discussed.Methods: 60 patients of failure IVF -ET were randomly divided into two groups:experiment group and COS group.We observed endometrial thickness,types and blood flow.Results:The endometrial thickness in experiment group was obviously increased(P0.05).After treatment,endometrial number of type A and type B in experiment group was increased(P0.05 ).RI of endometria in experiment group after treatment was obviously lower than that before treatment(P0.05 ). The blood flow of endometria was improved(P0.05).Compared with control group,there was significant difference(P0.05 ).The success rate in experiment group was higher than that in control group(P0.05).Conclusions:The method for invigorating kidney and activating blood and regulating menstruation can improve the endometrial thickness and blood flow so as to improve the endometrial receptivity,thus the success rat of IVF-ET can be improved.
机构地区 宁波市中医院
出处 《中华中医药学刊》 CAS 2013年第1期154-156,共3页 Chinese Archives of Traditional Chinese Medicine
基金 浙江省中医药管理局基金资助项目(2011ZA097)
关键词 补肾活血调周法 子宫内膜容受性 体外受精-胚胎移植 method for invigorating kidney and activating blood and regulating menstruation endometrial receptivity IVF-ET
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