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新型口服抗凝药在急性冠脉综合征中的应用 被引量:7

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摘要 血栓形成在急性冠脉综合征(ACS)发生、发展过程中起着重要作用。目前,作用于凝血连锁反应不同水平的新型抗凝药物已被研究并应用于预防深静脉血栓、房颤卒中以及ACS患者二级预防,特别是口服直接凝血酶抑制剂(希美加群、达比加群,AZD0837)以及口服直接Xa抑制剂(阿哌沙班、利伐沙班、darexaban、edoxaban、betrixaban等)是目前公认比华法林更安全、便捷的替代品。达比加群、阿哌沙班、利伐沙班、darexaban已在ACS患者中进行临床试验。
作者 金厦 殷跃辉
出处 《国际心血管病杂志》 2013年第1期34-37,共4页 International Journal of Cardiovascular Disease
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参考文献24

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