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二维斑点追踪技术评价不同PTH水平尿毒症患者左室心肌纵向应变及扭转运动 被引量:3

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摘要 目的:应用超声二维斑点追踪成像技术(STI)评价不同甲状旁腺激素(PTH)水平尿毒症患者的左室心肌纵向应变及扭转运动。方法:44例左室射血分数正常(LVEF>50%)的尿毒症患者(尿毒症组)根据PTH水平分为A组(PTH<正常值上限3倍)、B组(PTH>正常值上限3倍),22例健康志愿者作为对照组,对所有研究对象行斑点追踪应变成像分析,在心尖四腔、三腔、二腔长轴切面观获得左心室内、外膜下心肌纵向应变,在左室基底部、心尖部短轴切面观获得内、外膜心肌旋转、扭转角度,并比较3组间各指标变化情况。结果:(1)与对照组相比,尿毒症组左心室心内膜下心肌及整体纵向应变峰值减低,差异有统计学意义(P<0.05或P<0.01);外膜心肌纵向应变峰值减低仅在B组有统计学差异(P<0.05);与A组比较,B组仅内膜心肌纵向应变峰值减低(P<0.05)。(2)与对照组相比,尿毒症组左室整体及内、外膜心肌扭转角度均有减低,除A组膜心肌减低无统计学意义外,余均有统计学意义(P<0.05或P<0.01);与A组比较,B组内膜心肌扭转角度减低,差异有统计学意义(P<0.05),外膜心肌及整体扭转角度虽减低,但差异无统计学意义(P>0.05)。结论:STI技术能准确定量评估LVEF正常的尿毒症患者不同PTH水平心肌损伤变化,PTH水平较高者心肌功能损害较重。
出处 《实用医学杂志》 CAS 北大核心 2013年第3期407-410,共4页 The Journal of Practical Medicine
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参考文献8

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