摘要
目的比较用间接电极法测定血清和肝素钠抗凝血浆电解质浓度的差别,探讨肝素钠抗凝血浆电解质浓度的正常参考值。方法采用罗氏MUDULARISE900模块式电解质分析仪检测70例体检者血清和肝素钠抗凝血浆的电解质浓度。结果血清与肝素抗凝血浆的K+、Na+、Cl-的测定结果差异有统计学意义(P<0.01),平均差值分别为0.24、1.42、0.94mmol/L,相对偏差分别为5.60%、0.99%和0.89%。Na+和Cl-差别小,相对偏差小于1%,在临床上无实际意义;K+的差异已超过5%,且相对恒定。统计1739例健康体检者肝素钠抗凝血浆电解质浓度,以x±2s为正常参考质范围,则K+:3.27～4.67mmol/L,Na+:137.9～147.5mmol/L,Cl-:99.2～110.8mmol/L。结论肝素钠是一种较理想的电解质抗凝剂,适合于电解质的测定,但是肝素钠抗凝血浆K+明显低于血清,不能沿用血清的正常参考值,建议各实验室建立自已的正常参考范围。
Objective To compare the difference of serum and heparin sodium anticoagulation plasma electrolyte concentration by indirect electrode method,and to explore the normal reference values of heparin sodium anticoagulation plasma electrolyte con centration. Methods Using the Roche MUDULAR ISE900 modular electrolyte analyzer to test 70 healthy persons electrolyte in se rum and heparin sodium anticoagulant plasma. Results The difference of K＋,Na＋ and CI- lenels were statistically significant（P〈 0.01） ,The average difference of the serum and plasma K＋ , Na＋ and CI- were 0.24 mmol/L 1.42 mmol/L and 0.94 mmol/L re spectively,and the relative deviation were 5.6% ,0.99% and 0.89%. The difference of Na＋ and CI was small and the relative devi ation were less than 1%,which no practical significance was in clinic;while the difference of the K＋ in serum and plasma has excee- ded 5 ~ and constant relatively. We analyzed the concentration of plasma electrolyte in 1 739 healthy examination adults. The normal reference value was X±2s,then K＋ （3.27-4.67）mmol/L Na＋ （ 137.9-- 147.5）mmol/L Cl （99.2-- 110.8）mmol/L Conclusion Heparin was an ideal anticoagulant,which was suitable for the determination of electrolyte. However, the plasma K4 was signifi- cantly lower than that in serum,which have been unable to use the normal reference values of serum. Every laboratory should estab- lish their own normal reference range.
出处
《国际检验医学杂志》
CAS
2012年第21期2614-2615,共2页
International Journal of Laboratory Medicine
关键词
血清
血浆
肝素钠
电解质
参考值
serum
plasma
heparin sodium
electrolyte
reference value
