摘要
目的獉獉:了解云南省美沙酮门诊受治者HIV新发感染率及其影响因素。方法獉獉:于2008年10月招募HIV血清抗体阴性的美沙酮门诊受治者1139名进入队列,6个月后随访并进行血清学检测确定HIV新发感染率。将结果进行χ2检验及帕松回归分析。结果獉獉:6个月后随访894名调查对象,观察总人年为505.25人年,HIV阳转12人,HIV新发感染率为2.38/100人年。影响因素有:临沧地区门诊,"输入带有HIV的血液或血液制品会感染HIV"知识点答错,未了解或接受过免费安全套发放服务,了解或接受过机会性感染治疗、抗病毒治疗的调查对象HIV新发感染率较高。结论獉獉:美沙酮门诊受治者HIV新发感染率低于一般静脉吸毒人员。在美沙酮门诊加强艾滋病知识的培训,各种服务获得途径的宣传,以及扩大安全套免费发放的范围和数量,对于降低HIV新发感染率有意义。
Objective：To investigate the incidence and risk factors of HIV infection among methadone maintenance treatment（MMT）clients in Yunnan Province.Methods：A prospective cohort of 1139 HIV-negative MMT clients was developed in October 2008.The cohort was followed up after six months with questionnaires and blood tests for HIV.Chi-square tests and Poisson regression were used for results analysis.Results：Eight hundred and ninety four MMT clients remained in the cohort and were followed for a total of 505.25 person-years.The HIV incidence was 2.38 /100 person-years.It is found that the HIV incidence rates were significantly higher among those came from Lincang MMT clinic,those who gave wrong answer to the question ＂One can get infection of HIV through transfusions of infected blood or blood factors＂,those who had not heard of or received free condom delivery,and those who had heard of or received the services of opportunistic infections treatment and anti-retroviral treatment.Conclusion：The HIV incidence among MMT clients is lower than that of the general injection drug users（IDUs）.It is necessary to inform the HIV/AIDS treatment services,reinforce the training on HIV/AIDS knowledge and distribute free condoms in MMT clinics.
出处
《中国药物依赖性杂志》
CAS
CSCD
2012年第6期467-470,共4页
Chinese Journal of Drug Dependence
