摘要
目的探讨T2加权成像与FLAIR成像两种不同MRI成像方法在恶性胶质瘤靶区勾画方面的区别。方法 选择37例脑恶性胶质瘤患者,在4种预后因素相同或相似的条件下,随机分为两组,进行影像融合并勾画靶区。A组采用T2加权成像,共20例;B组采用FLAIR序列,共17例,分别比较靶区体积、周围正常组织剂量及复发模式。结果 在靶区体积方面,采用FLAIR成像,靶区范围更大,二者之间差异有统计学意义(P<0.05);在周围正常组织剂量及复发模式方面,二者之间差异无统计学意义(P值均>0.05)。结论 T2加权与FLAIR成像均可用于恶性胶质瘤初始靶区勾画,二者间在肿瘤复发模式方面无显著差异。
Objective To compare T2 and FLAIR sequences in the delineation of target of high grade gliomas. Methods Thirty-seven patients with high grade gliomas were divided into two groups depending on different prognostic factors. Their MRIs were fused with the treatment planning CTs. T2 weighted MRIs were used to define CTV1 for Group A, while FLAIR sequences were used for Group B. The CTV1 volumes, dose of adjacent critical structures and recurrence model of the two groups were compared. Results The FLAIR CTVs were significantly larger than T2 CTVs （ P 〈 0.01 ）. There was no difference in the dose of adjacent critical structures using T2 or FLAIR. There was no statistical difference in the percentage of failure using T2 or FLAIR. Conclusion Both T2 and FLAIR sequences can be used in the delineation of target in the radiation of malignant gliomas. There was no statistical difference in the recurrence modals of the tumors.
出处
《实用肿瘤杂志》
CAS
2013年第1期79-81,共3页
Journal of Practical Oncology
关键词
神经胶质瘤
放射疗法
磁共振成像
辐射剂量
复发
病例对照研究
glioma/radiotherapy
megnetic resonance imaging
radiation dosage
recurrence
case-control studies
