摘要
目的探讨血清CRP和外周血WBC计数、N%对小儿急性感染性腹泻的鉴别诊断价值,为小儿急性感染性腹泻早期鉴别诊断提供依据。方法对2010年6月-2011年9月蚌埠医学院一附院儿科确诊的141例小儿急性感染性腹泻(其中细菌性痢疾15例,大肠埃希菌肠炎21例,轮状病毒肠炎105例)临床资料进行分析。结果在感染性腹泻急性期,细菌性痢疾组、大肠埃希菌肠炎组和轮状病毒肠炎组血清CRP水平分别为112.1 mg/L、13.7 mg/L和5.17 mg/L,三组间差异有统计学意义(P<0.05);细菌性痢疾组和大肠埃希菌肠炎组WBC计数、N%均明显高于轮状病毒肠炎组,差异有统计学意义(均P<0.05),而细菌性痢疾组WBC计数、N%与大肠埃希菌肠炎组比较,差异无统计学意义(P>0.05)。结论 CRP、WBC计数和N%都是小儿感染性腹泻有意义的感染指标,其中以CRP最为敏感。因此,检测血CRP水平,结合临床表现有助于小儿感染性腹泻的早期诊断及鉴别诊断,减少误诊,对临床合理使用及避免滥用抗生素具有重要意义。
Objective To study the values of serum CRP,peripheral blood WBC count and N% in the differential diagnosis of children with acute infectious diarrhea, for early differential diagnosis of children with acute infectious diarrhea provides the ba-sis. Methods The clinical data of 141 cases of children with acute infectious diarrhea diagnosed in the department of pediatrics of the first hospital ＇affiliated to Bengbu Medical College from Jun. 2010 to Sep. 2011 were analyzed. According to the Infection type the clinical data, they were divided into 3 groups： bacterial dysentery group （n = 15 ） , Eseherichia eoli enteritis group （n = 21 ）, rotavirus enteritis group （n = 105 ）. Results In the acute phase of infection diarrhea, the serum CRP levels of the three groups： enteritis： bacillary dysentery group, eseheriehia coli enteritis group and rotavirus enteritis group were 112.1,13.7 and 5.17 rag/L, respectively. The difference of the three groups was statistically significant （ P 〈 0.05 ）. The WBC count, N% of bac-terial dysentery group and escherichia eoli enteritis group were significantly higher than those of rotavirus enteritis groups, the difference were statistically significant（ P 〈 0.05 ）, and the WBC count, N% of bacterial dysentery group compared with that of escheriehia coli enteritis, the difference was not statistically significant（ P 〉 0.05 ）. Conclusion The CRP, WBC count and N% were meaningful indicators of infection for acute infectious diarrhea, which the most sensitive was CRP. Therefore, the detection of blood CRP levels, in combination with the clinical manifestations of pediatric infectious enteritis, contributed to early diagnosis and differential diagnosis in pediatric infectious enteritis and reduce misdiagnosis, and clinical reasonable use antibiotics and avoid the abuse of antibiotics.
出处
《中华全科医学》
2013年第2期246-248,共3页
Chinese Journal of General Practice
