摘要
髋关节发育不良(DDH)是婴幼儿时期一种常见的骨科疾病,发病率为1‰～2‰。其是由股骨头和(或)髋臼的大小、形态、取向和(或)组织构成异常导致,通常指关节囊松弛和(或)髋臼太浅。DDH可导致膝关节不稳定、关节疼痛、步态异常及早发型骨性关节炎,因此早期预防、早期诊断和早期治疗显得尤为重要。预防该病必须了解病因,而遗传因素是DDH的重要病因之一。
Developmental dysplasia of the hip（DDH） is a common skeletal disease during the period of infant and child, and its morbidity is nearly 1%o-2%. Hip dysplasia refers to an anomaly in the size, shape, o- rientation, or organization of the femoral head, acetabulum, or both. This disease usually comprises shallow ac- etabulum and/or lax joint capsule. Hip instability,joint pain, gait abnormalities and premature arthritis are common clinical signs. It is important to prevent, diagnose and treat DDH as early as possible. More about the etiopathogenesis should be learned for the prevention, and genetic factor is one of the most important etiologi- cal factors of the disease.
出处
《医学综述》
2013年第2期252-255,共4页
Medical Recapitulate
关键词
髋关节发育不良
基因多态性
病例对照研究
Developmental dysplasia of the hip
Gene polymorphism
Case-control study
