摘要
目的研究经腹腔镜胆总管切开取石T管引流术(LCTD)后,拔除T管出现胆漏的处理办法;在临床常规方法的基础上,探讨生物蛋白胶封堵T管窦道漏口的可行性。方法研究对象为LCTD术后,拔除T管出现胆漏的患者36例,按照随机分组原则分为2组。对照组18例,拔除T管出现胆漏后,行禁食水、胃肠减压、抑酸、抑酶、抗感染治疗,同时经胆道镜T管窦道尿管置入或经十二指肠镜鼻胆管引流;研究组18例,拔除T管出现胆漏后,除禁食水、胃肠减压、抑酸、抑酶、抗感染治疗、经胆道镜T管窦道尿管置入或经十二指肠镜鼻胆管引流外,经胆道镜从T管窦道置入生物蛋白胶堵漏,封闭窦道撕裂或未完全愈合处。统计、对比两组患者的病情恢复情况。结果对照组单纯使用T管窦道尿管置入或鼻胆管引流,腹膜炎体征恢复慢,治疗时间长,费用高,其中2例患者行二次手术;研究组在使用T管窦道尿管置入或鼻胆管引流的基础上,加用生物蛋白胶封堵窦道漏口,腹膜炎体征恢复快,治疗时间短,费用低,无二次手术患者。两组比较,各指标差异有统计学意义(P<0.05)。结论对于拔除T管后出现胆漏的患者,除禁食水、胃肠减压、抑酸、抑酶、抗感染、再次T管窦道置入尿管引流或鼻胆管引流外,联合胆道镜植入生物蛋白胶堵漏治疗拔T管后胆漏,较单纯使用尿管引流或鼻胆管引流效果更好,恢复快,费用低,值得推广。
Objective To study the treatment approach of biliary fistula after removal of T tube, in the process of laparoscopic choledocholithotomy with T tube drainage （LCTD）. And, on the basis of clinical routine methods, to discuss the feasibility of fibrin glue to block T tube sinus orifice. Methods The research objects were collected for the LCTD postoperatively, biliary fistula found after the removal of T tube. Thirty-six cases were randomly divided into 2 groups. A control group of 18 cases, when bile leakage found after the removal of the T tube, food and water fasting, gastrointestinal decompression, acid and enzyme inhibition, anti infection treatments were carded out. At the same time, the endoscopic T tube sinus catheter was placed or endoscopic nasobiliary drainage undergone. The study group of 18 cases, when bile leakage found after the removal of the T tube, in addition to the routine methods carried out same as the control group, fibrin glue sealant was implanted through T tube sinus by choledochofiberscopy, to block the sinus laceration or the incomplete healing. Recovery conditions in patients of two groups were compared and statistically analyzed. Results In the control group, signs of peritonitis recovered more slowly, treatment processed for a longer time, and costs higher. Two patients underwent a second operation. In the study group, signs of peritonitis recovery more quickly, with shorter treatment time and lower cost, no second operation needed in all patients. Comparison between the two groups, each index had a significant difference （P 〈0.05）. Conclusion For patients with bile leakage after the removal of the T tube, in addition to the routine methods of food and water fasting, gastrointestinal decompression, acid and enzyme inhibition, anti infection, endoscopic T tube sinus catheter placed or endoscopic nasobiliary drainage undergone, the implantation of fibrin glue sealant can improve the recovery speed, with lower cost, no second operation, which is worth popularizing.
出处
《肝胆胰外科杂志》
CAS
2013年第1期16-19,共4页
Journal of Hepatopancreatobiliary Surgery
关键词
T管
胆漏
胆道镜
生物蛋白胶
T tube
biliary fistula
biliary tract endoscope
fibrin glue sealant
