摘要
视网膜血管瘤样增生（RAP）是湿性年龄相关性黄斑变性（AMD）的一种特殊类型，其基本病变为新生血管形成，但与起源于脉络膜的新生血管性疾病如隐匿性脉络膜新生血管（CNV）、经典型CNV及息肉状脉络膜新生血管病变（PCV）不同，多数学者认为RAP的新生血管起源于视网膜深层毛细血管网。目前对此病的认识尚不足，临床上存在诊断困难、疗效不理想且预后差等问题。近年来，随着对湿性AMD的深入研究以及吲哚青绿血管造影（ICGA）技术和新一代光学相干断层扫描（OCT）技术的应用，对RAP有了进一步的认识。就RAP的分期、组织学起源及组织病理学、自然病程、眼底表现特点、鉴别诊断及治疗现状进行综述。
Retinal angiomatous proliferation （RAP） is a special type of age-related macular degeneration （AMD） with a pathological process of neovascularization. Different with several types of neovascular AMD,the new blood vessel in RAP is believed to originate from the inner retinal circulation. Because of inadequate knowledge, there still exist some limited understanding for this disease, such as its clinical diagnosis, therapy effectiveness and its poor prognosis. The newest interpretation about RAP was based on the findings of indocyanine green angiography （ICGA） and the first generation of optical coherence tomography （OCT） imaging system. The stage, histogenesis, histopathology,nature process, fundus findings,differentiating diagnosis and trcatrnent of RAP were reviewed.
出处
《中华实验眼科杂志》
CAS
CSCD
北大核心
2013年第1期101-104,共4页
Chinese Journal Of Experimental Ophthalmology
