摘要
目的探讨慢性乙型肝炎、肝硬化、肝癌肝病患者P-选择素水平检测血小板的活性状态。方法检测45例乙型肝炎患者和24例乙肝合并肝硬化、肝癌患者P-选择素水平并与正常对照组30例进行对比分析。结果肝炎患者、肝硬化、肝癌组的P-选择素水平显著高于正常对照组(P<0.05),差异均有统计学意义(P<0.05)。结论乙型肝炎患者和乙肝合并肝硬化、肝癌患者的P-选择素水平均升高,且在肝癌组中P-选择素所测水平最高,患者血浆P-选择素的增高对肝病病情有一定的反映。
Objective To investigate the platelet activity by the measuring P selectin in patients with chronic hepatitis B, cirrhosis and hepatic carcinoma. Methods The levels of P selectin in 45 patients with hepatitis B alone, 14 patients with hepatitis B complicated by cirrhosis, 10 patients with hepatitis B complicated by hepatic carcinoma and 30 normal persons were measured and analyzed. Results The levels of P selectin in hepatitis B group, cirrhosis group and hepatic carcinoma group were higher than that in control group, and there was a statistically significant difference in the levels of P selectin between groups. Conclusion The P selectin in patients with hepatitis alone or complicated by cirrhosis and hepatic carcinoma is increased, with the highest level in hepatic carcinoma group, indicating that the increased P selcctin is associated with the state of hepatic disease.
出处
《宁夏医学杂志》
CAS
2012年第12期1215-1216,共2页
Ningxia Medical Journal
基金
宁夏银川市科技计划项目(201040)
关键词
乙型肝炎
肝硬化
肝癌
P-选择素
Hepatitis B
Cirrhosis
Hepatic carcinoma
P selectin
