摘要
[目的]探讨先天性巨结肠术后并发小肠结肠炎的危险因素。[方法]选取湖南省儿童医院2009年1月1日至2010年12月31日期间在新生儿外科住院的年龄3个月内经手术治疗的先天性巨结肠惠儿98例。采用单因素logistic回归和多因素logistic回归统计分析术后并发小肠结肠炎的危险因素。[结果]98例患儿中,男78例(79.6%);女20例(20.4%)。治愈96例(98%);死亡2例(2%)。20例(20.4%)术后发生小肠结肠炎,单因素logistic回归分析表明,并发小肠结肠炎的危险因素主要是营养不良、肠梗阻、牛奶过敏、肺炎、肠神经节细胞减少和败血症。多因素logistic回归分析表明,其危险因素主要是营养不良、肠梗阻、肠神经节细胞减少和肺炎。[结论]小肠结肠炎是先天性巨结肠术后常见而且严重的并发症,营养不良、肠梗阻、肠神经节细胞减少和肺炎可能是术后小肠结肠炎的独立危险因素。改善患儿营养状况,解除肠梗阻因素和保护肠道黏膜可减少该并发症的发生。
[Objective] To explore the risk factors of enterocolitis after surgery of Hirschsprung's disease. [Methods] A total of 98 pediatric patients with Hirschsprung's disease undergoing the operation within 3 months in neonate surgery department of children's hospital of Hunan province from Jan. 2009 to Dec. 2010 were chosen. Univariate logistic regression and multifactor logistic regression analysis were used to analyze the risk factors of enterocolitis after operation. [Results] Among 98 pediatric patients, 78 patients(79.6%) were male and 20 patients(20.40//oo) were female. The 96 patients(98%) were cured, and 2 patients(2%) died. The 20 patients(20.4%) were complicated with enterocolitis after operation. Univariate logistic regression analysis showed that the main risk lactors of complicated enterocolitis were malnutrition, intestinal obstruction, milk allergy, pneumonia, hypoganglionosis and septicemia. Multifactor logistic regression analysis showed that the risk factors were malnutrition, intestinal obstruction, hypoganglionosis and pneumonia. [Conclusion] Entero- colitis is the common and serious complication for Hirschsprung's disease after operation. Malnutrition, intesti- nal obstruction, hypoganglionosis and pneumonia may be the independent risk factors of enterocolitis after operation. Improving nutrition, removing intestinal obstruction and protecting mucous membrane of pediatric patients can reduce the incidence of the complication.
出处
《医学临床研究》
CAS
2012年第12期2325-2327,共3页
Journal of Clinical Research