摘要
目的观察胆囊术后使用甲氧氯普胺促进肛门排气及抑制恶心、呕吐的临床效果。方法选择开腹胆囊切除术80例,随机分为A、B两组,每组40人。A组为给药组,手术结束时硬膜外腔注射甲氧氯普胺10 mg+生理盐水至5 mL;以后每隔12小时静脉给甲氧氯普胺10 mg。直到肛门排气时停用。B组为对照组,手术结束时硬膜外腔注射生理盐水5 mL。以后每隔12小时静脉给生理盐水1 mL。直到肛门排气时停用。对比观察两组第一次肛门排气的时间及术后恶心、呕吐的发生病例数。结果 A组肛门排气时间明显早于B组,恶心呕吐的病例数明显少于B组。经χ2检验,差异有显著性意义(P<0.05)。结论甲氧氯普胺用于胆囊术后能明显促进肛门排气及抑制恶心呕吐不良反应的发生。
Objective To observe the clinical effect of metoclopramide in promoting anal exhaust and inhibiting nausea and vomiting after eholecyst surgery. Methods Eighty patients receiving open cholecystectomy were randomly divided into group A and group B, with 40 patients in each group. Group A, namely the medication group, was given epidu- ral injection of 10 mg of metoclopramide ＋ saline to 5 ml in the end of the surgery; Then 10 mg of metoclopramide was administered intravenously every other 12 hours until anal exhaust. Group B, namely the control group, was given epidural injection of 5 ml of saline; Then 1 ml of saline was administered intravenously every other 12 hours until anal exhaust. The time of first anal exhaust and the postoperative number of cases of nausea and vomiting of the two groups were compared. Results Group A was significantly earlier than group B in the time of anal exhaust and signifi- cantly fewer in the number of cases of nausea and vomiting. ~test indicated statistically significant differences （P 〈 0.05）. Conclusion Metoclopramide can significantly promote anal exhaust and inhibit the occurrence of nausea and vomiting after cholecyst surgery.
出处
《中国现代医生》
2013年第2期118-119,共2页
China Modern Doctor
关键词
甲氧氯普胺
胆囊术后
肛门排气
恶心
呕吐
Metoclopramide
Post-cholecyst surgery
Anal exhaust
Nausea
Vomiting
