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舒克菲治疗反流性咽喉炎临床观察

Clinical observation on treating reflux laryngopharyngitis with sucralfate
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摘要 目的:本文旨在评估舒克菲治疗反流性咽喉炎的临床疗效。方法:门诊病人84例,分为3组,每组28例。A组服用舒克菲;B组服用西米替丁;C组是联合用药组,服用舒克菲和西米替丁。结果:A组显效18例,有效6例,总有效率为85.71%;B组显效15例,有效7例,总有效率为78.57%;C组显效22例,有效4例,总有效率为92.86%。舒克菲加用西米替丁与舒克菲单独用药差异无显著性(P>0.05)。结论:舒克菲作为粘膜保护剂治疗反流性咽喉炎,有其独特的药理作用,疗效肯定,未见明显副反应。 Objective: To evaluate the efficacy of sucralfate in the treatment of reflux laryngopharyngitis. Method: Eighty-four outpatients were divided evenly into 3 groups. Patients in Group A received sucralfate,patients in Group B received cimetidine and patients in Group C received both sucralfate and cimetidine. Results:In Group A,there were 18 patients improved markedly and 6 patients improved,the global effective rate was 85. 71%. In Group B,there were 15 patients improved markedly,and 7 patients improved,the global effecive rate was 78. 57%. In Group C,there were 22 patients improved markedly,4 patients improved,the global effecive rate was 92. 86%. The difference in efficacies between sucralfate alone and sucralfate together with cimetidine was not significant(P>0. 05). Conclusion: As a mucous membrane protective agent,sucralfate has unique pharmacological effects,it is effctive in the treatment of reflux laryngopharyngitis without obvious side effect.
机构地区 上海市纺三医院
出处 《上海医药》 CAS 2000年第6期13-15,共3页 Shanghai Medical & Pharmaceutical Journal
关键词 舒克菲 反流性食管炎 咽喉炎 药肠疗法 临床观察 sucralf ate reflux esophagitis laryngopharyngitis
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