摘要
目的观察丹术消异方联合腹腔镜手术治疗轻度子宫内膜异位症不孕患者的临床疗效及对血清IL-8的影响。方法将50例不孕且经腹腔镜证实为轻度子宫内膜异位症患者随机分为两组,治疗组25例,腹腔镜术后排卵前用丹术消异方治疗,排卵后口服助孕3号丸;对照组25例,腹腔镜术后不予药物治疗。所有患者均于术后B超监测排卵,并指导同房。观察两组患者术后3个月临床症状改善情况;术后3个月、6个月的受孕情况;术后3个月IL-8的变化。结果术后3个月,痛经、腰骶不适、肛门坠胀感、性交痛、下腹痛症状均有明显改善,治疗组症状改善情况明显优于对照组(P<0.05)。两组患者术后3个月、6个月妊娠率、流产率经统计学比较,有显著性差异(P<0.05)。术后3个月,两组IL-8均较治疗前降低(P<0.05),治疗组比对照组降低更明显(P<0.05)。结论丹术消异方联合腹腔镜手术治疗轻度子宫内膜异位症不孕,能明显改善患者的主要临床症状,并提高受孕率,其作用机制可能与调节机体免疫,降低血清IL-8水平有关。
Objective To observe Danzhuxiaoyifang combined with laparoscopy on serum IL-8 of infertile patients with mild endometriosis.Methods 50 patients were divided into 2 groups,the treat group was given Traditional Chinese Medicine after laparoscope,while the control group was only accepted laparoscopy.The improvement of clinical symptoms,pregnancy rate,and serum IL-8 was observed.Results The effect in the treat group was better than that in the control group（P0.05）.Conclusions Danzhuxiaoyifang combined with laparoscopy in the treatment of mild endometriosis infertility may improve the clinical symptoms,increase the pregnancy rate,its mechanism may be related to the regulation of the immune,decrease serum IL-8.
出处
《湖北中医药大学学报》
2012年第6期21-23,共3页
Journal of Hubei University of Chinese Medicine
基金
广东省科技厅资助课题(编号:2010B060900066)
