摘要
慢性乙型肝炎患者感染HBV的主要途径为母婴传播,母婴传播的机制不完全明确。阻断母婴传播的措施应该贯穿从孕前到婴儿出生后的全过程,HBsAg阳性孕妇娩出的新生儿应在24 h内尽早进行主-被动联合免疫,以尽可能减少围产期感染及哺乳期感染,乙型肝炎高病毒载量（≥10~6IU/ml）孕期应抗病毒治疗,以降低宫内传播的发生率。
Vertical transmission is the main route of hepatitis B virus（HBV） infection in patients with chronic hepatitis B（CHB）.However, the mechanisms underlying the vertical transmission process remain to be fully elucidated.Measures to prevent mother - to - child transmission should be carried out during gestation,delivery,and the postnatal period.In order to reduce perinatal transmission and postnatal transmission through infected breast milk,newborns whose mothers tested positive for hepatitis B surface antigen（HBsAg） should be given active/passive immunization within 24 hours of delivery.In order to reduce the incidence of intrauterine transmission,pregnant women with CHB（HBV DNA≥10~6 IU/ml） should be given antiviral treatment.
出处
《临床肝胆病杂志》
CAS
2012年第12期959-960,I0001,共3页
Journal of Clinical Hepatology
关键词
肝炎病毒
乙型
疾病传播
垂直
免疫
主动
免疫
被动法
hepatitis B virus
disease transmission
vertical
immunity active
immunization
passive
