帕瑞昔布钠多模式镇痛及预防苏醒期躁动在OSAHS患者中的应用被引量：1

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摘要目的观察帕瑞昔布钠对阻塞性睡眠呼吸暂停低通气综合征（OSAHS）患者行悬雍垂腭咽成形术（UPPP）手术苏醒期躁动程度及疼痛治疗效果的影响。方法将60例ASAⅡ~Ⅲ级,年龄20~65岁,择期OSAHS患者行UPPP手术的患者,随机分为A、B两组,A组为空白对照组,分别于术前、术后给予生理盐水2mL;B组为实验组,给予帕瑞昔布钠40mg。观察两组术中芬太尼和瑞芬太尼用量及苏醒后带管期意识恢复时间及RASS、术后多时点VAS评分,记录24h内患者对术后镇痛的满意度。结果 B组术中瑞芬太尼,及芬太尼用量均小于A组,且具有统计学意义。RASS评分B组中重度发生例数明显多于A组,有显著性差异。术后各时点B组VAS评分均低于A组,且具有统计学意义。结论帕瑞昔布钠对OSAHS患者UPPP手术患者有良好的止痛效果,并可减轻全麻术后苏醒期躁动。

作者李红日王姝君刘烨

机构地区吉林省长春市二道区人民医院吉林省长春市绿园区疾病预防控制中心吉林省长春市二道区疾病预防控制中心

出处《中国医药指南》 2012年第35期151-152,共2页 Guide of China Medicine

关键词帕瑞昔布钠多模式镇痛苏醒期躁动 OSAHS

分类号 R614 [医药卫生—麻醉学]

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