摘要
皮质下缺血性血管病(SIVD)是一组由脑部小血管疾病导致的以皮质下多发性腔隙性脑梗死和脑白质病变为主要病理损害的缺血性脑血管病。SIVD可以导致认知功能受损,还可以伴发皮质下损害症候,如情感障碍、步态障碍、排尿功能障碍、假性延髓麻痹,以及执行功能异常等。有研究表明,上述皮质下损害特征可能是血管性痴呆的早期标志,对老年人的生活质量产生严重影响。该文将对SIVD导致的皮质下损害特征,及其与日常生活能力受损之间的关系做一综述。
Subcortical ischemic vascular disease（SIVD） is a group of ischemic cerebrovascular diseases caused by small-vessel damage.The major pathological feature includes multiple subcortical lacunar infarction and white matter lesions.SIVD may result in cognitive impairment.Some subcortical damage features may occur in SIVD,such as emotional incontinence,gait disturbance,deficiency in bladder control,pseudobulbar palsy and executive dysfunction.It has been reported that subcortical features in the elderly may be the early signs of vascular dementia and seriously influence the activities of daily life.This article reviews the subcortical features caused by SIVD and the relations between the subcortical features and the activities of daily life.
出处
《安徽医药》
CAS
2012年第12期1737-1739,共3页
Anhui Medical and Pharmaceutical Journal
基金
安徽省教育厅自然科学基金重点项目(NoKJ2011A170)
关键词
认知损害
皮质下损害
痴呆
血管性
脑梗死
cognitive impairment
subcortical signs
dementia
vascular
brain infarction
